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Inhibition of Adult Hippocampal Neurogenesis Plays a Role in Sevoflurane-Induced Cognitive Impairment in Aged Mice Through Brain-Derived Neurotrophic Factor/Tyrosine Receptor Kinase B and Neurotrophin-3/Tropomyosin Receptor Kinase C Pathways
Sevoflurane anesthesia induces cognitive impairment, which may lead to perioperative neurocognitive disorders (PND). However, the factors and molecular mechanism underlying this impairment remains unclear. Adult hippocampal neurogenesis (AHN) in the subgranular zone of the hippocampus has been impli...
Autores principales: | Xu, Lichi, Guo, Yanjing, Wang, Gongming, Sun, Guoqing, Sun, Wei, Li, Jingjing, Li, Xinlei, Wu, Jiangnan, Zhang, Mengyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931760/ https://www.ncbi.nlm.nih.gov/pubmed/35309893 http://dx.doi.org/10.3389/fnagi.2022.782932 |
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