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Inhibition of Adult Hippocampal Neurogenesis Plays a Role in Sevoflurane-Induced Cognitive Impairment in Aged Mice Through Brain-Derived Neurotrophic Factor/Tyrosine Receptor Kinase B and Neurotrophin-3/Tropomyosin Receptor Kinase C Pathways

Sevoflurane anesthesia induces cognitive impairment, which may lead to perioperative neurocognitive disorders (PND). However, the factors and molecular mechanism underlying this impairment remains unclear. Adult hippocampal neurogenesis (AHN) in the subgranular zone of the hippocampus has been impli...

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Detalles Bibliográficos
Autores principales: Xu, Lichi, Guo, Yanjing, Wang, Gongming, Sun, Guoqing, Sun, Wei, Li, Jingjing, Li, Xinlei, Wu, Jiangnan, Zhang, Mengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931760/
https://www.ncbi.nlm.nih.gov/pubmed/35309893
http://dx.doi.org/10.3389/fnagi.2022.782932

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