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Focal-onset seizure due to left internal carotid artery dissection in the context of confounding hyperglycaemia

A 36-year-old diabetic woman presented to hospital with a seizure that started with shaking of the right hand which sequentially progressed to the entire right side of the body with associated loss of consciousness. Capillary Blood Glucose was 29 mmol/L. HbA1c was 133 mmol/L. Non-contrast computeris...

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Autores principales: Moulder, Zachary, Kosela, Monika, Zafar, M Ahtsham, Jha, Abhinav, Gopal, Karthik, Pandey, Anmol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931818/
https://www.ncbi.nlm.nih.gov/pubmed/35316987
http://dx.doi.org/10.1093/omcr/omac028
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author Moulder, Zachary
Kosela, Monika
Zafar, M Ahtsham
Jha, Abhinav
Gopal, Karthik
Pandey, Anmol
author_facet Moulder, Zachary
Kosela, Monika
Zafar, M Ahtsham
Jha, Abhinav
Gopal, Karthik
Pandey, Anmol
author_sort Moulder, Zachary
collection PubMed
description A 36-year-old diabetic woman presented to hospital with a seizure that started with shaking of the right hand which sequentially progressed to the entire right side of the body with associated loss of consciousness. Capillary Blood Glucose was 29 mmol/L. HbA1c was 133 mmol/L. Non-contrast computerised tomography (CT) scan of the brain was normal suggesting that the cause of her seizure was hyperglycaemia. However, Magnetic Resonance Imaging (MRI) of the brain showed infarcts in the left paracentral lobule and caudate nucleus. It also identified loss of signal flow void in the intracranial segment of the left internal carotid artery (ICA) raising the suspicion for thrombosis secondary to dissection. This was later confirmed on CT angiogram. This case demonstrates how the initial CT Head was non-diagnostic. We stress the importance of taking a careful seizure history and subsequently obtaining an MRI scan to fully exclude structural pathology.
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spelling pubmed-89318182022-03-21 Focal-onset seizure due to left internal carotid artery dissection in the context of confounding hyperglycaemia Moulder, Zachary Kosela, Monika Zafar, M Ahtsham Jha, Abhinav Gopal, Karthik Pandey, Anmol Oxf Med Case Reports Case Report A 36-year-old diabetic woman presented to hospital with a seizure that started with shaking of the right hand which sequentially progressed to the entire right side of the body with associated loss of consciousness. Capillary Blood Glucose was 29 mmol/L. HbA1c was 133 mmol/L. Non-contrast computerised tomography (CT) scan of the brain was normal suggesting that the cause of her seizure was hyperglycaemia. However, Magnetic Resonance Imaging (MRI) of the brain showed infarcts in the left paracentral lobule and caudate nucleus. It also identified loss of signal flow void in the intracranial segment of the left internal carotid artery (ICA) raising the suspicion for thrombosis secondary to dissection. This was later confirmed on CT angiogram. This case demonstrates how the initial CT Head was non-diagnostic. We stress the importance of taking a careful seizure history and subsequently obtaining an MRI scan to fully exclude structural pathology. Oxford University Press 2022-03-16 /pmc/articles/PMC8931818/ /pubmed/35316987 http://dx.doi.org/10.1093/omcr/omac028 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Moulder, Zachary
Kosela, Monika
Zafar, M Ahtsham
Jha, Abhinav
Gopal, Karthik
Pandey, Anmol
Focal-onset seizure due to left internal carotid artery dissection in the context of confounding hyperglycaemia
title Focal-onset seizure due to left internal carotid artery dissection in the context of confounding hyperglycaemia
title_full Focal-onset seizure due to left internal carotid artery dissection in the context of confounding hyperglycaemia
title_fullStr Focal-onset seizure due to left internal carotid artery dissection in the context of confounding hyperglycaemia
title_full_unstemmed Focal-onset seizure due to left internal carotid artery dissection in the context of confounding hyperglycaemia
title_short Focal-onset seizure due to left internal carotid artery dissection in the context of confounding hyperglycaemia
title_sort focal-onset seizure due to left internal carotid artery dissection in the context of confounding hyperglycaemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931818/
https://www.ncbi.nlm.nih.gov/pubmed/35316987
http://dx.doi.org/10.1093/omcr/omac028
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