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Tunga penetrans causing a rapidly progressing foot ulcer in a patient with uncontrolled type 2 diabetes mellitus

Tungiasis is a parasitic disease resulting from infestation by a female flea Tunga penetrans. The parasites are endemic in the tropics and can infect patients with diabetes mellitus (DM). Augmented by uncontrolled hyperglycemia and pre-existing neuropathy, the parasite may trigger a locally spreadin...

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Autores principales: Ebrahim, Ashabilan A, Mpango, Elisia P, Temba, Joseph A, Abbas, Zulfiqarali G, Mashili, Fredirick L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931829/
https://www.ncbi.nlm.nih.gov/pubmed/35316989
http://dx.doi.org/10.1093/omcr/omac016
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author Ebrahim, Ashabilan A
Mpango, Elisia P
Temba, Joseph A
Abbas, Zulfiqarali G
Mashili, Fredirick L
author_facet Ebrahim, Ashabilan A
Mpango, Elisia P
Temba, Joseph A
Abbas, Zulfiqarali G
Mashili, Fredirick L
author_sort Ebrahim, Ashabilan A
collection PubMed
description Tungiasis is a parasitic disease resulting from infestation by a female flea Tunga penetrans. The parasites are endemic in the tropics and can infect patients with diabetes mellitus (DM). Augmented by uncontrolled hyperglycemia and pre-existing neuropathy, the parasite may trigger a locally spreading inflammation, which may aggravate the trauma introduced during its extraction, leading into a rapidly progressing foot ulcer. To the best of our knowledge, no such cases in patients with type 2 diabetes have ever been published from Tanzania and likely none worldwide. This case report shows that, in diabetic patients, the wound resulting from the extraction of T. penetrans may get infected and aggravated by the ongoing inflammatory reaction, rapidly evolve into limb-threatening condition and mortality. Preventive measures are necessary and should be emphasized in patients with DM. Studies are needed to increase our understanding of the pathophysiology, proper management and sequalae of ulcers of this nature.
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spelling pubmed-89318292022-03-21 Tunga penetrans causing a rapidly progressing foot ulcer in a patient with uncontrolled type 2 diabetes mellitus Ebrahim, Ashabilan A Mpango, Elisia P Temba, Joseph A Abbas, Zulfiqarali G Mashili, Fredirick L Oxf Med Case Reports Case Report Tungiasis is a parasitic disease resulting from infestation by a female flea Tunga penetrans. The parasites are endemic in the tropics and can infect patients with diabetes mellitus (DM). Augmented by uncontrolled hyperglycemia and pre-existing neuropathy, the parasite may trigger a locally spreading inflammation, which may aggravate the trauma introduced during its extraction, leading into a rapidly progressing foot ulcer. To the best of our knowledge, no such cases in patients with type 2 diabetes have ever been published from Tanzania and likely none worldwide. This case report shows that, in diabetic patients, the wound resulting from the extraction of T. penetrans may get infected and aggravated by the ongoing inflammatory reaction, rapidly evolve into limb-threatening condition and mortality. Preventive measures are necessary and should be emphasized in patients with DM. Studies are needed to increase our understanding of the pathophysiology, proper management and sequalae of ulcers of this nature. Oxford University Press 2022-03-16 /pmc/articles/PMC8931829/ /pubmed/35316989 http://dx.doi.org/10.1093/omcr/omac016 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ebrahim, Ashabilan A
Mpango, Elisia P
Temba, Joseph A
Abbas, Zulfiqarali G
Mashili, Fredirick L
Tunga penetrans causing a rapidly progressing foot ulcer in a patient with uncontrolled type 2 diabetes mellitus
title Tunga penetrans causing a rapidly progressing foot ulcer in a patient with uncontrolled type 2 diabetes mellitus
title_full Tunga penetrans causing a rapidly progressing foot ulcer in a patient with uncontrolled type 2 diabetes mellitus
title_fullStr Tunga penetrans causing a rapidly progressing foot ulcer in a patient with uncontrolled type 2 diabetes mellitus
title_full_unstemmed Tunga penetrans causing a rapidly progressing foot ulcer in a patient with uncontrolled type 2 diabetes mellitus
title_short Tunga penetrans causing a rapidly progressing foot ulcer in a patient with uncontrolled type 2 diabetes mellitus
title_sort tunga penetrans causing a rapidly progressing foot ulcer in a patient with uncontrolled type 2 diabetes mellitus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931829/
https://www.ncbi.nlm.nih.gov/pubmed/35316989
http://dx.doi.org/10.1093/omcr/omac016
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