DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer

Gastric cancer (GC) is a very common malignancy with a poor prognosis, and its occurrence and development are closely related to epigenetic modifications. Methylation of DNA before or during gastric cancer is an interesting research topic. This article reviews the studies on DNA methylation related...

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Autores principales: Zeng, Yunqing, Rong, Huimin, Xu, Jianwei, Cao, Ruyue, Li, Shuhua, Gao, Yanjing, Cheng, Baoquan, Zhou, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931997/
https://www.ncbi.nlm.nih.gov/pubmed/35309131
http://dx.doi.org/10.3389/fgene.2022.823905
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author Zeng, Yunqing
Rong, Huimin
Xu, Jianwei
Cao, Ruyue
Li, Shuhua
Gao, Yanjing
Cheng, Baoquan
Zhou, Tao
author_facet Zeng, Yunqing
Rong, Huimin
Xu, Jianwei
Cao, Ruyue
Li, Shuhua
Gao, Yanjing
Cheng, Baoquan
Zhou, Tao
author_sort Zeng, Yunqing
collection PubMed
description Gastric cancer (GC) is a very common malignancy with a poor prognosis, and its occurrence and development are closely related to epigenetic modifications. Methylation of DNA before or during gastric cancer is an interesting research topic. This article reviews the studies on DNA methylation related to the cause, diagnosis, treatment, and prognosis of gastric cancer and aims to find cancer biomarkers to solve major human health problems.
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spelling pubmed-89319972022-03-19 DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer Zeng, Yunqing Rong, Huimin Xu, Jianwei Cao, Ruyue Li, Shuhua Gao, Yanjing Cheng, Baoquan Zhou, Tao Front Genet Genetics Gastric cancer (GC) is a very common malignancy with a poor prognosis, and its occurrence and development are closely related to epigenetic modifications. Methylation of DNA before or during gastric cancer is an interesting research topic. This article reviews the studies on DNA methylation related to the cause, diagnosis, treatment, and prognosis of gastric cancer and aims to find cancer biomarkers to solve major human health problems. Frontiers Media S.A. 2022-03-04 /pmc/articles/PMC8931997/ /pubmed/35309131 http://dx.doi.org/10.3389/fgene.2022.823905 Text en Copyright © 2022 Zeng, Rong, Xu, Cao, Li, Gao, Cheng and Zhou. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Zeng, Yunqing
Rong, Huimin
Xu, Jianwei
Cao, Ruyue
Li, Shuhua
Gao, Yanjing
Cheng, Baoquan
Zhou, Tao
DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer
title DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer
title_full DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer
title_fullStr DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer
title_full_unstemmed DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer
title_short DNA Methylation: An Important Biomarker and Therapeutic Target for Gastric Cancer
title_sort dna methylation: an important biomarker and therapeutic target for gastric cancer
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931997/
https://www.ncbi.nlm.nih.gov/pubmed/35309131
http://dx.doi.org/10.3389/fgene.2022.823905
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