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In situ antigen modification-based target-redirected universal chimeric antigen receptor T (TRUE CAR-T) cell therapy in solid tumors

BACKGROUND: Chimeric antigen receptor (CAR)-T cell therapy has demonstrated remarkable success in the treatment of hematologic malignancies, while the success has not yet been replicated in solid tumors. To some extent, the disappointing results can be attributed to the paucity and heterogeneity of...

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Detalles Bibliográficos
Autores principales:	Sun, Zhichen, Li, Rutian, Shen, Yun, Tan, Siyi, Ding, Naiqing, Xu, Ruihan, Wang, Xinyue, Wei, Jia, Liu, Baorui, Meng, Fanyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Rapid Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932190/ https://www.ncbi.nlm.nih.gov/pubmed/35303900 http://dx.doi.org/10.1186/s13045-022-01246-y

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