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Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness

BACKGROUND: We recently showed that fucosyltransferase 8 (FUT8)-mediated core fucosylation of transforming growth factor-β receptor enhances its signaling and promotes breast cancer invasion and metastasis. However, the complete FUT8 target glycoproteins and their downstream signaling networks criti...

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Detalles Bibliográficos
Autores principales: Tu, Cheng-Fen, Li, Fu-An, Li, Ling-Hui, Yang, Ruey-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932202/
https://www.ncbi.nlm.nih.gov/pubmed/35303925
http://dx.doi.org/10.1186/s13058-022-01513-3