HER3 Is an Actionable Target in Advanced Prostate Cancer

It has been recognized for decades that ERBB signaling is important in prostate cancer, but targeting ERBB receptors as a therapeutic strategy for prostate cancer has been ineffective clinically. However, we show here that membranous HER3 protein is commonly highly expressed in lethal prostate cance...

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Detalles Bibliográficos
Autores principales: Gil, Veronica, Miranda, Susana, Riisnaes, Ruth, Gurel, Bora, D’Ambrosio, Mariantonietta, Vasciaveo, Alessandro, Crespo, Mateus, Ferreira, Ana, Brina, Daniela, Troiani, Martina, Sharp, Adam, Sheehan, Beshara, Christova, Rossitza, Seed, George, Figueiredo, Ines, Lambros, Maryou, Dolling, David, Rekowski, Jan, Alajati, Abdullah, Clarke, Matthew, Pereira, Rita, Flohr, Penny, Fowler, Gemma, Boysen, Gunther, Sumanasuriya, Semini, Bianchini, Diletta, Rescigno, Pasquale, Aversa, Caterina, Tunariu, Nina, Guo, Christina, Paschalis, Alec, Bertan, Claudia, Buroni, Lorenzo, Ning, Jian, Carreira, Suzanne, Workman, Paul, Swain, Amanda, Califano, Andrea, Shen, Michael M., Alimonti, Andrea, Neeb, Antje, Welti, Jonathan, Yuan, Wei, de Bono, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Translational Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932336/
https://www.ncbi.nlm.nih.gov/pubmed/34753775
http://dx.doi.org/10.1158/0008-5472.CAN-21-3360

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