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Differential metabolism of arsenicals regulates Fps1-mediated arsenite transport
Arsenic is an environmental toxin that exists mainly as pentavalent arsenate and trivalent arsenite. Both forms activate the yeast SAPK Hog1 but with different consequences. We describe a mechanism by which cells distinguish between these arsenicals through one-step metabolism to differentially regu...
Autores principales: | Lee, Jongmin, Levin, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932518/ https://www.ncbi.nlm.nih.gov/pubmed/35139143 http://dx.doi.org/10.1083/jcb.202109034 |
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