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Differential metabolism of arsenicals regulates Fps1-mediated arsenite transport

Arsenic is an environmental toxin that exists mainly as pentavalent arsenate and trivalent arsenite. Both forms activate the yeast SAPK Hog1 but with different consequences. We describe a mechanism by which cells distinguish between these arsenicals through one-step metabolism to differentially regu...

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Detalles Bibliográficos
Autores principales: Lee, Jongmin, Levin, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932518/
https://www.ncbi.nlm.nih.gov/pubmed/35139143
http://dx.doi.org/10.1083/jcb.202109034

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