Closing the gap: Tricellulin/α-catenin interaction maintains epithelial integrity at vertices

Tricellular junctions play a critical role in regulating epithelial barrier function. In this issue, Cho et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202009037) demonstrate a novel interaction between tricellulin and α-catenin, which connects tricellular junctions to the actomyosin cytosk...

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Detalles Bibliográficos
Autores principales: van den Goor, Lotte, Miller, Ann L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932530/
https://www.ncbi.nlm.nih.gov/pubmed/35191951
http://dx.doi.org/10.1083/jcb.202202009
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author van den Goor, Lotte
Miller, Ann L.
author_facet van den Goor, Lotte
Miller, Ann L.
author_sort van den Goor, Lotte
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description Tricellular junctions play a critical role in regulating epithelial barrier function. In this issue, Cho et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202009037) demonstrate a novel interaction between tricellulin and α-catenin, which connects tricellular junctions to the actomyosin cytoskeleton, thus supporting the epithelial barrier at cell vertices.
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spelling pubmed-89325302022-10-04 Closing the gap: Tricellulin/α-catenin interaction maintains epithelial integrity at vertices van den Goor, Lotte Miller, Ann L. J Cell Biol Spotlight Tricellular junctions play a critical role in regulating epithelial barrier function. In this issue, Cho et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202009037) demonstrate a novel interaction between tricellulin and α-catenin, which connects tricellular junctions to the actomyosin cytoskeleton, thus supporting the epithelial barrier at cell vertices. Rockefeller University Press 2022-02-22 /pmc/articles/PMC8932530/ /pubmed/35191951 http://dx.doi.org/10.1083/jcb.202202009 Text en © 2022 Van den Goor and Miller https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
van den Goor, Lotte
Miller, Ann L.
Closing the gap: Tricellulin/α-catenin interaction maintains epithelial integrity at vertices
title Closing the gap: Tricellulin/α-catenin interaction maintains epithelial integrity at vertices
title_full Closing the gap: Tricellulin/α-catenin interaction maintains epithelial integrity at vertices
title_fullStr Closing the gap: Tricellulin/α-catenin interaction maintains epithelial integrity at vertices
title_full_unstemmed Closing the gap: Tricellulin/α-catenin interaction maintains epithelial integrity at vertices
title_short Closing the gap: Tricellulin/α-catenin interaction maintains epithelial integrity at vertices
title_sort closing the gap: tricellulin/α-catenin interaction maintains epithelial integrity at vertices
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932530/
https://www.ncbi.nlm.nih.gov/pubmed/35191951
http://dx.doi.org/10.1083/jcb.202202009
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