Vascular heterogeneity: VEGF receptors make blood vessels special

Karaman et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20210565) examined the differential effects of the conditional deletion of genes encoding each VEGF receptor, VEGFR1, VEGFR2 and VEGFR 3, as well as combinations thereof in mice. The results highlight the crosstalk between receptors in d...

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Detalles Bibliográficos
Autores principales: Li, Pin, Ferrara, Napoleone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Insights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932539/
https://www.ncbi.nlm.nih.gov/pubmed/35085381
http://dx.doi.org/10.1084/jem.20212539
Descripción
Sumario:Karaman et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20210565) examined the differential effects of the conditional deletion of genes encoding each VEGF receptor, VEGFR1, VEGFR2 and VEGFR 3, as well as combinations thereof in mice. The results highlight the crosstalk between receptors in different organs and emphasize the importance of VEGF receptor expression and interplay in vascular heterogeneity.

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