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Vascular heterogeneity: VEGF receptors make blood vessels special
Karaman et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20210565) examined the differential effects of the conditional deletion of genes encoding each VEGF receptor, VEGFR1, VEGFR2 and VEGFR 3, as well as combinations thereof in mice. The results highlight the crosstalk between receptors in d...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932539/ https://www.ncbi.nlm.nih.gov/pubmed/35085381 http://dx.doi.org/10.1084/jem.20212539 |
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author | Li, Pin Ferrara, Napoleone |
author_facet | Li, Pin Ferrara, Napoleone |
author_sort | Li, Pin |
collection | PubMed |
description | Karaman et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20210565) examined the differential effects of the conditional deletion of genes encoding each VEGF receptor, VEGFR1, VEGFR2 and VEGFR 3, as well as combinations thereof in mice. The results highlight the crosstalk between receptors in different organs and emphasize the importance of VEGF receptor expression and interplay in vascular heterogeneity. |
format | Online Article Text |
id | pubmed-8932539 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-89325392022-09-07 Vascular heterogeneity: VEGF receptors make blood vessels special Li, Pin Ferrara, Napoleone J Exp Med Insights Karaman et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20210565) examined the differential effects of the conditional deletion of genes encoding each VEGF receptor, VEGFR1, VEGFR2 and VEGFR 3, as well as combinations thereof in mice. The results highlight the crosstalk between receptors in different organs and emphasize the importance of VEGF receptor expression and interplay in vascular heterogeneity. Rockefeller University Press 2022-01-24 /pmc/articles/PMC8932539/ /pubmed/35085381 http://dx.doi.org/10.1084/jem.20212539 Text en © 2022 Li and Ferrara https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Insights Li, Pin Ferrara, Napoleone Vascular heterogeneity: VEGF receptors make blood vessels special |
title | Vascular heterogeneity: VEGF receptors make blood vessels special |
title_full | Vascular heterogeneity: VEGF receptors make blood vessels special |
title_fullStr | Vascular heterogeneity: VEGF receptors make blood vessels special |
title_full_unstemmed | Vascular heterogeneity: VEGF receptors make blood vessels special |
title_short | Vascular heterogeneity: VEGF receptors make blood vessels special |
title_sort | vascular heterogeneity: vegf receptors make blood vessels special |
topic | Insights |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932539/ https://www.ncbi.nlm.nih.gov/pubmed/35085381 http://dx.doi.org/10.1084/jem.20212539 |
work_keys_str_mv | AT lipin vascularheterogeneityvegfreceptorsmakebloodvesselsspecial AT ferraranapoleone vascularheterogeneityvegfreceptorsmakebloodvesselsspecial |