Lipid-loaded tumor-associated macrophages sustain tumor growth and invasiveness in prostate cancer

Tumor-associated macrophages (TAMs) are correlated with the progression of prostatic adenocarcinoma (PCa). The mechanistic basis of this correlation and therapeutic strategies to target TAMs in PCa remain poorly defined. Here, single-cell RNA sequencing was used to profile the transcriptional landsc...

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Detalles Bibliográficos
Autores principales: Masetti, Michela, Carriero, Roberta, Portale, Federica, Marelli, Giulia, Morina, Nicolò, Pandini, Marta, Iovino, Marta, Partini, Bianca, Erreni, Marco, Ponzetta, Andrea, Magrini, Elena, Colombo, Piergiuseppe, Elefante, Grazia, Colombo, Federico Simone, den Haan, Joke M.M., Peano, Clelia, Cibella, Javier, Termanini, Alberto, Kunderfranco, Paolo, Brummelman, Jolanda, Chung, Matthew Wai Heng, Lazzeri, Massimo, Hurle, Rodolfo, Casale, Paolo, Lugli, Enrico, DePinho, Ronald A., Mukhopadhyay, Subhankar, Gordon, Siamon, Di Mitri, Diletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932635/
https://www.ncbi.nlm.nih.gov/pubmed/34919143
http://dx.doi.org/10.1084/jem.20210564

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