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Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli
Humans predominantly explore their environment by moving their eyes. To optimally communicate and process visual information, neural activity needs to be coordinated with the execution of eye movements. We investigated the coordination between visual exploration and interareal neural communication b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932656/ https://www.ncbi.nlm.nih.gov/pubmed/35302856 http://dx.doi.org/10.1126/sciadv.abl6037 |
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author | Staudigl, Tobias Minxha, Juri Mamelak, Adam N. Gothard, Katalin M. Rutishauser, Ueli |
author_facet | Staudigl, Tobias Minxha, Juri Mamelak, Adam N. Gothard, Katalin M. Rutishauser, Ueli |
author_sort | Staudigl, Tobias |
collection | PubMed |
description | Humans predominantly explore their environment by moving their eyes. To optimally communicate and process visual information, neural activity needs to be coordinated with the execution of eye movements. We investigated the coordination between visual exploration and interareal neural communication by analyzing local field potentials and single neuron activity in patients with epilepsy. We demonstrated that during the free viewing of images, neural communication between the human amygdala and hippocampus is coordinated with the execution of eye movements. The strength and direction of neural communication and hippocampal saccade-related phase alignment were strongest for fixations that landed on human faces. Our results argue that the state of the human medial temporal lobe network is selectively coordinated with motor behavior. Interareal neural communication was facilitated for social stimuli as indexed by the category of the attended information. |
format | Online Article Text |
id | pubmed-8932656 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-89326562022-03-31 Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli Staudigl, Tobias Minxha, Juri Mamelak, Adam N. Gothard, Katalin M. Rutishauser, Ueli Sci Adv Neuroscience Humans predominantly explore their environment by moving their eyes. To optimally communicate and process visual information, neural activity needs to be coordinated with the execution of eye movements. We investigated the coordination between visual exploration and interareal neural communication by analyzing local field potentials and single neuron activity in patients with epilepsy. We demonstrated that during the free viewing of images, neural communication between the human amygdala and hippocampus is coordinated with the execution of eye movements. The strength and direction of neural communication and hippocampal saccade-related phase alignment were strongest for fixations that landed on human faces. Our results argue that the state of the human medial temporal lobe network is selectively coordinated with motor behavior. Interareal neural communication was facilitated for social stimuli as indexed by the category of the attended information. American Association for the Advancement of Science 2022-03-18 /pmc/articles/PMC8932656/ /pubmed/35302856 http://dx.doi.org/10.1126/sciadv.abl6037 Text en Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Neuroscience Staudigl, Tobias Minxha, Juri Mamelak, Adam N. Gothard, Katalin M. Rutishauser, Ueli Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli |
title | Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli |
title_full | Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli |
title_fullStr | Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli |
title_full_unstemmed | Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli |
title_short | Saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli |
title_sort | saccade-related neural communication in the human medial temporal lobe is modulated by the social relevance of stimuli |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932656/ https://www.ncbi.nlm.nih.gov/pubmed/35302856 http://dx.doi.org/10.1126/sciadv.abl6037 |
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