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The Burden of Typhoid Fever in Sub-Saharan Africa: A Perspective
While typhoid fever has largely been eliminated in high-income regions which have developed modern water, sanitation, and hygiene facilities, it remains a significant public health burden resulting in morbidity and mortality among millions of individuals in resource-constrained settings. Prevention...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932916/ https://www.ncbi.nlm.nih.gov/pubmed/35308424 http://dx.doi.org/10.2147/RRTM.S282461 |
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author | Kim, Cara Lynn Cruz Espinoza, Ligia Maria Vannice, Kirsten S Tadesse, Birkneh Tilahun Owusu-Dabo, Ellis Rakotozandrindrainy, Raphaël Jani, Ilesh V Teferi, Mekonnen Bassiahi Soura, Abdramane Lunguya, Octavie Steele, A Duncan Marks, Florian |
author_facet | Kim, Cara Lynn Cruz Espinoza, Ligia Maria Vannice, Kirsten S Tadesse, Birkneh Tilahun Owusu-Dabo, Ellis Rakotozandrindrainy, Raphaël Jani, Ilesh V Teferi, Mekonnen Bassiahi Soura, Abdramane Lunguya, Octavie Steele, A Duncan Marks, Florian |
author_sort | Kim, Cara Lynn |
collection | PubMed |
description | While typhoid fever has largely been eliminated in high-income regions which have developed modern water, sanitation, and hygiene facilities, it remains a significant public health burden resulting in morbidity and mortality among millions of individuals in resource-constrained settings. Prevention and control efforts are needed that integrate several high-impact interventions targeting facilities and infrastructure, including those addressing improvements in sanitation, access to safe water, and planned urbanization, together with parallel efforts directed at effective strategies for use of typhoid conjugate vaccines (TCV). The use of TCVs is a critical tool with the potential of having a rapid impact on typhoid fever disease burden; their introduction will also serve as an important strategy to combat evolving antimicrobial resistance to currently available typhoid fever treatments. Well-designed epidemiological surveillance studies play a critical role in establishing the need for, and monitoring the impact of, typhoid fever control and prevention strategies implemented by public health authorities. Here, we present a perspective based on a narrative review of the impact of typhoid fever on morbidity and mortality in sub-Saharan Africa and discuss ongoing surveillance activities and the role of vaccination in prevention and control efforts. |
format | Online Article Text |
id | pubmed-8932916 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-89329162022-03-19 The Burden of Typhoid Fever in Sub-Saharan Africa: A Perspective Kim, Cara Lynn Cruz Espinoza, Ligia Maria Vannice, Kirsten S Tadesse, Birkneh Tilahun Owusu-Dabo, Ellis Rakotozandrindrainy, Raphaël Jani, Ilesh V Teferi, Mekonnen Bassiahi Soura, Abdramane Lunguya, Octavie Steele, A Duncan Marks, Florian Res Rep Trop Med Review While typhoid fever has largely been eliminated in high-income regions which have developed modern water, sanitation, and hygiene facilities, it remains a significant public health burden resulting in morbidity and mortality among millions of individuals in resource-constrained settings. Prevention and control efforts are needed that integrate several high-impact interventions targeting facilities and infrastructure, including those addressing improvements in sanitation, access to safe water, and planned urbanization, together with parallel efforts directed at effective strategies for use of typhoid conjugate vaccines (TCV). The use of TCVs is a critical tool with the potential of having a rapid impact on typhoid fever disease burden; their introduction will also serve as an important strategy to combat evolving antimicrobial resistance to currently available typhoid fever treatments. Well-designed epidemiological surveillance studies play a critical role in establishing the need for, and monitoring the impact of, typhoid fever control and prevention strategies implemented by public health authorities. Here, we present a perspective based on a narrative review of the impact of typhoid fever on morbidity and mortality in sub-Saharan Africa and discuss ongoing surveillance activities and the role of vaccination in prevention and control efforts. Dove 2022-03-14 /pmc/articles/PMC8932916/ /pubmed/35308424 http://dx.doi.org/10.2147/RRTM.S282461 Text en © 2022 Kim et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Kim, Cara Lynn Cruz Espinoza, Ligia Maria Vannice, Kirsten S Tadesse, Birkneh Tilahun Owusu-Dabo, Ellis Rakotozandrindrainy, Raphaël Jani, Ilesh V Teferi, Mekonnen Bassiahi Soura, Abdramane Lunguya, Octavie Steele, A Duncan Marks, Florian The Burden of Typhoid Fever in Sub-Saharan Africa: A Perspective |
title | The Burden of Typhoid Fever in Sub-Saharan Africa: A Perspective |
title_full | The Burden of Typhoid Fever in Sub-Saharan Africa: A Perspective |
title_fullStr | The Burden of Typhoid Fever in Sub-Saharan Africa: A Perspective |
title_full_unstemmed | The Burden of Typhoid Fever in Sub-Saharan Africa: A Perspective |
title_short | The Burden of Typhoid Fever in Sub-Saharan Africa: A Perspective |
title_sort | burden of typhoid fever in sub-saharan africa: a perspective |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8932916/ https://www.ncbi.nlm.nih.gov/pubmed/35308424 http://dx.doi.org/10.2147/RRTM.S282461 |
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