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Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions

Temporal molecular changes in ageing mammalian organs are of relevance to disease aetiology because many age-related diseases are linked to changes in the transcriptional and epigenetic machinery that regulate gene expression. We performed quantitative proteome analysis of chromatin-enriched protein...

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Detalles Bibliográficos
Autores principales: Oliviero, Giorgio, Kovalchuk, Sergey, Rogowska-Wrzesinska, Adelina, Schwämmle, Veit, Jensen, Ole N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933006/
https://www.ncbi.nlm.nih.gov/pubmed/35259090
http://dx.doi.org/10.7554/eLife.73524