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Pharmacokinetics and safety of inhaled ivermectin in mice as a potential COVID-19 treatment

Pharmacokinetic limitations associated with oral ivermectin may limit its success as a potential COVID-19 treatment based on in vitro experiments which demonstrate antiviral efficacy against SARS-CoV-2 at high concentrations. Targeted delivery to the lungs is a practical way to overcome these limita...

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Detalles Bibliográficos
Autores principales: Albariqi, Ahmed H., Wang, Yuncheng, Chang, Rachel Yoon Kyung, Quan, Diana H., Wang, Xiaonan, Kalfas, Stefanie, Drago, John, Britton, Warwick J., Chan, Hak-Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933053/
https://www.ncbi.nlm.nih.gov/pubmed/35314278
http://dx.doi.org/10.1016/j.ijpharm.2022.121688