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The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression
The epithelial to mesenchymal transition (EMT), a process that is aberrantly activated in cancer and facilitates metastasis to distant organs, requires coordinated transcriptional and post-transcriptional control of gene expression. The tumor-suppressive RNA binding protein, hnRNP-E1, regulates spli...
Autores principales: | Howley, Breege V., Mohanty, Bidyut, Dalton, Annamarie, Grelet, Simon, Karam, Joseph, Dincman, Toros, Howe, Philip H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933277/ https://www.ncbi.nlm.nih.gov/pubmed/35102251 http://dx.doi.org/10.1038/s41388-022-02199-9 |
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