Cargando…

Active demethylation upregulates CD147 expression promoting non-small cell lung cancer invasion and metastasis

Non-small cell lung cancer (NSCLC) is a fatal disease, and its metastatic process is poorly understood. Although aberrant methylation is involved in tumor progression, the mechanisms underlying dynamic DNA methylation remain to be elucidated. It is significant to study the molecular mechanism of NSC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liao, Cheng-Gong, Liang, Xiao-Hua, Ke, Yuan, Yao, Li, Liu, Man, Liu, Ze-Kun, He, Lin, Guo, Yi-Xiao, Bian, Huijie, Chen, Zhi-Nan, Kong, Ling-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933279/ https://www.ncbi.nlm.nih.gov/pubmed/35132181 http://dx.doi.org/10.1038/s41388-022-02213-0

Ejemplares similares

System analysis of the regulation of the immune response by CD147 and FOXC1 in cancer cell lines
por: Shang, Yu-Kui, et al.
Publicado: (2018)

Doxycycline Inducible Chimeric Antigen Receptor T Cells Targeting CD147 for Hepatocellular Carcinoma Therapy
por: Zhang, Ren-Yu, et al.
Publicado: (2019)

Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis
por: Lv, Jian-Jun, et al.
Publicado: (2021)

Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner
por: Zhang, Tian, et al.
Publicado: (2020)

CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis
por: Shi, Wen-Pu, et al.
Publicado: (2018)

Upregulation of CD147 Promotes Metastasis of Cholangiocarcinoma by Modulating the Epithelial-to-Mesenchymal Transitional Process
por: Dana, Paweena, et al.
Publicado: (2017)

CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis
por: Wu, Jiao, et al.
Publicado: (2022)

Basolateral CD147 induces hepatocyte polarity loss by E‐cadherin ubiquitination and degradation in hepatocellular carcinoma progress
por: Lu, Meng, et al.
Publicado: (2018)

CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma
por: Wang, Shi-Jie, et al.
Publicado: (2020)

Interaction of CD147 and human epididymis protein 4 promotes invasion and metastasis of ovarian cancer
por: Gao, Lingling, et al.
Publicado: (2021)

Activation of TGF-β1-CD147 positive feedback loop in hepatic stellate cells promotes liver fibrosis
por: Li, Hai-Yan, et al.
Publicado: (2015)

Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinoma
por: Wu, Jiao, et al.
Publicado: (2014)

Novel Functions of CD147 in the Mitochondria Exacerbates Melanoma Metastasis
por: Lu, Lixia, et al.
Publicado: (2021)

Promoter hypomethylation up-regulates CD147 expression through increasing Sp1 binding and associates with poor prognosis in human hepatocellular carcinoma
por: Kong, Ling-Min, et al.
Publicado: (2011)

Chimeric antigen receptor T cells targeting CD147 for non-small cell lung cancer therapy
por: Chen, Xiao-Hong, et al.
Publicado: (2021)

CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes
por: Zhu, Ping, et al.
Publicado: (2006)

Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling
por: Xu, Bao-Qing, et al.
Publicado: (2016)

Involvement of HAb18G/CD147 in T cell activation and immunological synapse formation
por: Hu, Jinsong, et al.
Publicado: (2010)

Expression of COX-2, CD44v6 and CD147 and Relationship with Invasion and Lymph Node Metastasis in Hypopharyngeal Squamous Cell Carcinoma
por: Yang, Qing, et al.
Publicado: (2013)

Importance of N-Glycosylation on CD147 for Its Biological Functions
por: Bai, Yang, et al.
Publicado: (2014)

Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis
por: Zheng, H-C, et al.
Publicado: (2006)

A novel small-molecule compound targeting CD147 inhibits the motility and invasion of hepatocellular carcinoma cells
por: Fu, Zhi-guang, et al.
Publicado: (2016)

In Vitro and In Vivo Prostate Cancer Metastasis and Chemoresistance Can Be Modulated by Expression of either CD44 or CD147
por: Hao, Jingli, et al.
Publicado: (2012)

Demethylation of the MIR145 promoter suppresses migration and invasion in breast cancer
por: Liu, Shui-Yi, et al.
Publicado: (2017)

N-linked glycosylation at Asn152 on CD147 affects protein folding and stability: promoting tumour metastasis in hepatocellular carcinoma
por: Li, Jiang-Hua, et al.
Publicado: (2016)

N‐glycosylation by N‐acetylglucosaminyltransferase V enhances the interaction of CD147/basigin with integrin β1 and promotes HCC metastasis
por: Cui, Jian, et al.
Publicado: (2018)

Targeting CD147 for T to NK Lineage Reprogramming and Tumor Therapy
por: Geng, Jie-Jie, et al.
Publicado: (2017)

Expression of CD147 (EMMPRIN) on neutrophils in rheumatoid arthritis enhances chemotaxis, matrix metalloproteinase production and invasiveness of synoviocytes
por: Wang, Cong-Hua, et al.
Publicado: (2011)

CD147 blockade as a potential and novel treatment of graft rejection
por: Luan, Jing, et al.
Publicado: (2017)

CD98-induced CD147 signaling stabilizes the Foxp3 protein to maintain tissue homeostasis
por: Geng, JieJie, et al.
Publicado: (2021)

Purification of a polyclonal antibody against CD147 for ELISA using antigen-immunoaffinity chromatography
por: Liu, Shuangshuang, et al.
Publicado: (2017)

CD147 reinforces [Ca(2+)](i) oscillations and promotes oncogenic progression in hepatocellular carcinoma
por: Tang, Juan, et al.
Publicado: (2015)

CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells
por: Wang, Ke, et al.
Publicado: (2020)

Involvement of CD147 in overexpression of MMP-2 and MMP-9 and enhancement of invasive potential of PMA-differentiated THP-1
por: Zhou, Jun, et al.
Publicado: (2005)

The interaction of HAb18G/CD147 with integrin α6β1 and its implications for the invasion potential of human hepatoma cells
por: Dai, Jing-yao, et al.
Publicado: (2009)

The role of CD147 expression in prostate cancer: a systematic review and meta-analysis
por: Ye, Yun, et al.
Publicado: (2016)

Glucocorticoid Exposure of Preimplantation Embryos Increases Offspring Anxiety-Like Behavior by Upregulating miR-211-5p via Trpm1 Demethylation
por: Yuan, Hong-Jie, et al.
Publicado: (2022)

CD147 promotes glucose metabolism, invasion and metastasis via PI3K/AKT pathway in oral squamous cell carcinomas
por: Huang, Yi, et al.
Publicado: (2019)

Clinical Significance of CD147 in Children with Inflammatory Bowel Disease
por: Wang, Hongli, et al.
Publicado: (2020)

Discovery and Biological Evaluation of CD147 N-Glycan Inhibitors: A New Direction in the Treatment of Tumor Metastasis
por: Li, Wenqian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oaue1nm6nbnq5aqtirau4810kj