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The role of CD4 T cells in rejection of solid tumors
The focus in cancer immunotherapy has mainly been on CD8 T cells, as they can directly recognize cancer cells. CD4 T cells have largely been neglected, because most cancers lack MHC II expression and cannot directly be recognized by CD4 T cells. Yet, tumor antigens can be captured and cross-presente...
Autores principales: | Poncette, Lucia, Bluhm, Julia, Blankenstein, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933281/ https://www.ncbi.nlm.nih.gov/pubmed/34619457 http://dx.doi.org/10.1016/j.coi.2021.09.005 |
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