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Periocular Manifestation of Obstructive Sleep Apnea as a Novel Perioperative Screening Tool
PURPOSE: Obstructive sleep apnea (OSA) presents perioperative challenges with increased risk for complications. Floppy eyelid syndrome (FES) is associated with OSA yet has not been addressed perioperatively. The current standard for perioperative OSA screening includes assessing patient risk factors...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933341/ https://www.ncbi.nlm.nih.gov/pubmed/35091903 http://dx.doi.org/10.1007/s11695-021-05851-7 |
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author | Folsom, Megan Gigantelli, James Timperley, Brent Johnson, Kurtis Bagenda, Danstan Pang, Huiling Ellis, Sheila |
author_facet | Folsom, Megan Gigantelli, James Timperley, Brent Johnson, Kurtis Bagenda, Danstan Pang, Huiling Ellis, Sheila |
author_sort | Folsom, Megan |
collection | PubMed |
description | PURPOSE: Obstructive sleep apnea (OSA) presents perioperative challenges with increased risk for complications. Floppy eyelid syndrome (FES) is associated with OSA yet has not been addressed perioperatively. The current standard for perioperative OSA screening includes assessing patient risk factors or the STOP-BANG tool, which requires an active participant. We aimed to confirm a connection between FES and OSA in presurgical patients and develop a screening method appropriate for patients with perioperative OSA risk. MATERIALS AND METHODS: 162 presurgical pre-anesthesia clinic patients were enrolled. Screening questions determined eligibility. Those who were pregnant or aged < 19 were excluded. Control group included those with a STOP-BANG score < 3. Experimental group included those with BMI > 35 and OSA diagnosis. Examiners photographed participants’ eyes with vertical and horizontal retraction while two blinded ophthalmologists used a grading scale to review grade of eyelid laxity. RESULTS: Differences in habitus, ASA score, and hypertension as a comorbidity were significant. Sensitivity of FES screening was 52% (CI 37–66%) and specificity was 56% (CI 46–66%) for reviewer 1. For reviewer 2, sensitivity was 48% (CI 28–69%) and specificity was 72% (CI 60–81%). Negative predictive value was 86% (CI 81–90) for reviewer 1 and 88% (CI 83–92%) for reviewer 2. Inter-rater agreement was moderate. CONCLUSION: While specificity and sensitivity were lower than anticipated, negative predictive value was high. Given this strong negative predictive value, our findings indicate using eyelid retraction to screen for FES has perioperative clinical utility. These findings encourage further research addressing the connection of lid laxity/FES to OSA. KEY POINTS: • Aimed to investigate if a FES screening tool could identify perioperative OSA risk. • Negative predictive value for FES with OSA was 86%. • Observing periocular lid laxity has clinical utility; is feasible in any patient. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-8933341 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-89333412022-04-01 Periocular Manifestation of Obstructive Sleep Apnea as a Novel Perioperative Screening Tool Folsom, Megan Gigantelli, James Timperley, Brent Johnson, Kurtis Bagenda, Danstan Pang, Huiling Ellis, Sheila Obes Surg Original Contributions PURPOSE: Obstructive sleep apnea (OSA) presents perioperative challenges with increased risk for complications. Floppy eyelid syndrome (FES) is associated with OSA yet has not been addressed perioperatively. The current standard for perioperative OSA screening includes assessing patient risk factors or the STOP-BANG tool, which requires an active participant. We aimed to confirm a connection between FES and OSA in presurgical patients and develop a screening method appropriate for patients with perioperative OSA risk. MATERIALS AND METHODS: 162 presurgical pre-anesthesia clinic patients were enrolled. Screening questions determined eligibility. Those who were pregnant or aged < 19 were excluded. Control group included those with a STOP-BANG score < 3. Experimental group included those with BMI > 35 and OSA diagnosis. Examiners photographed participants’ eyes with vertical and horizontal retraction while two blinded ophthalmologists used a grading scale to review grade of eyelid laxity. RESULTS: Differences in habitus, ASA score, and hypertension as a comorbidity were significant. Sensitivity of FES screening was 52% (CI 37–66%) and specificity was 56% (CI 46–66%) for reviewer 1. For reviewer 2, sensitivity was 48% (CI 28–69%) and specificity was 72% (CI 60–81%). Negative predictive value was 86% (CI 81–90) for reviewer 1 and 88% (CI 83–92%) for reviewer 2. Inter-rater agreement was moderate. CONCLUSION: While specificity and sensitivity were lower than anticipated, negative predictive value was high. Given this strong negative predictive value, our findings indicate using eyelid retraction to screen for FES has perioperative clinical utility. These findings encourage further research addressing the connection of lid laxity/FES to OSA. KEY POINTS: • Aimed to investigate if a FES screening tool could identify perioperative OSA risk. • Negative predictive value for FES with OSA was 86%. • Observing periocular lid laxity has clinical utility; is feasible in any patient. GRAPHICAL ABSTRACT: [Image: see text] Springer US 2022-01-29 2022 /pmc/articles/PMC8933341/ /pubmed/35091903 http://dx.doi.org/10.1007/s11695-021-05851-7 Text en © The Author(s) 2022, corrected publication 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Contributions Folsom, Megan Gigantelli, James Timperley, Brent Johnson, Kurtis Bagenda, Danstan Pang, Huiling Ellis, Sheila Periocular Manifestation of Obstructive Sleep Apnea as a Novel Perioperative Screening Tool |
title | Periocular Manifestation of Obstructive Sleep Apnea as a Novel Perioperative Screening Tool |
title_full | Periocular Manifestation of Obstructive Sleep Apnea as a Novel Perioperative Screening Tool |
title_fullStr | Periocular Manifestation of Obstructive Sleep Apnea as a Novel Perioperative Screening Tool |
title_full_unstemmed | Periocular Manifestation of Obstructive Sleep Apnea as a Novel Perioperative Screening Tool |
title_short | Periocular Manifestation of Obstructive Sleep Apnea as a Novel Perioperative Screening Tool |
title_sort | periocular manifestation of obstructive sleep apnea as a novel perioperative screening tool |
topic | Original Contributions |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933341/ https://www.ncbi.nlm.nih.gov/pubmed/35091903 http://dx.doi.org/10.1007/s11695-021-05851-7 |
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