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Neoadjuvant Stereotactic Body Radiotherapy After Upfront Chemotherapy Improves Pathologic Outcomes Compared With Chemotherapy Alone for Patients With Borderline Resectable or Locally Advanced Pancreatic Adenocarcinoma Without Increasing Perioperative Toxicity

BACKGROUND: Patients with borderline resectable pancreatic cancer (BRPC) or locally advanced pancreatic cancer (LAPC) are at high risk of margin-positive resection. Neoadjuvant stereotactic body radiation therapy (SBRT) may help sterilize margins, but its additive benefit beyond neoadjuvant chemothe...

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Detalles Bibliográficos
Autores principales: Hill, Colin S., Rosati, Lauren M., Hu, Chen, Fu, Wei, Sehgal, Shuchi, Hacker-Prietz, Amy, Wolfgang, Christopher L., Weiss, Matthew J., Burkhart, Richard A., Hruban, Ralph H., De Jesus-Acosta, Ana, Le, Dung T., Zheng, Lei, Laheru, Daniel A., He, Jin, Narang, Amol K., Herman, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933354/
https://www.ncbi.nlm.nih.gov/pubmed/35129721
http://dx.doi.org/10.1245/s10434-021-11202-8