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Parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages

Understanding how populations adapt to abrupt environmental change is necessary to predict responses to future challenges, but identifying specific adaptive variants, quantifying their responses to selection and reconstructing their detailed histories is challenging in natural populations. Here, we...

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Autores principales: Fulgione, Andrea, Neto, Célia, Elfarargi, Ahmed F., Tergemina, Emmanuel, Ansari, Shifa, Göktay, Mehmet, Dinis, Herculano, Döring, Nina, Flood, Pádraic J., Rodriguez-Pacheco, Sofia, Walden, Nora, Koch, Marcus A., Roux, Fabrice, Hermisson, Joachim, Hancock, Angela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933414/
https://www.ncbi.nlm.nih.gov/pubmed/35304466
http://dx.doi.org/10.1038/s41467-022-28800-z
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author Fulgione, Andrea
Neto, Célia
Elfarargi, Ahmed F.
Tergemina, Emmanuel
Ansari, Shifa
Göktay, Mehmet
Dinis, Herculano
Döring, Nina
Flood, Pádraic J.
Rodriguez-Pacheco, Sofia
Walden, Nora
Koch, Marcus A.
Roux, Fabrice
Hermisson, Joachim
Hancock, Angela M.
author_facet Fulgione, Andrea
Neto, Célia
Elfarargi, Ahmed F.
Tergemina, Emmanuel
Ansari, Shifa
Göktay, Mehmet
Dinis, Herculano
Döring, Nina
Flood, Pádraic J.
Rodriguez-Pacheco, Sofia
Walden, Nora
Koch, Marcus A.
Roux, Fabrice
Hermisson, Joachim
Hancock, Angela M.
author_sort Fulgione, Andrea
collection PubMed
description Understanding how populations adapt to abrupt environmental change is necessary to predict responses to future challenges, but identifying specific adaptive variants, quantifying their responses to selection and reconstructing their detailed histories is challenging in natural populations. Here, we use Arabidopsis from the Cape Verde Islands as a model to investigate the mechanisms of adaptation after a sudden shift to a more arid climate. We find genome-wide evidence of adaptation after a multivariate change in selection pressures. In particular, time to flowering is reduced in parallel across islands, substantially increasing fitness. This change is mediated by convergent de novo loss of function of two core flowering time genes: FRI on one island and FLC on the other. Evolutionary reconstructions reveal a case where expansion of the new populations coincided with the emergence and proliferation of these variants, consistent with models of rapid adaptation and evolutionary rescue.
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spelling pubmed-89334142022-04-01 Parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages Fulgione, Andrea Neto, Célia Elfarargi, Ahmed F. Tergemina, Emmanuel Ansari, Shifa Göktay, Mehmet Dinis, Herculano Döring, Nina Flood, Pádraic J. Rodriguez-Pacheco, Sofia Walden, Nora Koch, Marcus A. Roux, Fabrice Hermisson, Joachim Hancock, Angela M. Nat Commun Article Understanding how populations adapt to abrupt environmental change is necessary to predict responses to future challenges, but identifying specific adaptive variants, quantifying their responses to selection and reconstructing their detailed histories is challenging in natural populations. Here, we use Arabidopsis from the Cape Verde Islands as a model to investigate the mechanisms of adaptation after a sudden shift to a more arid climate. We find genome-wide evidence of adaptation after a multivariate change in selection pressures. In particular, time to flowering is reduced in parallel across islands, substantially increasing fitness. This change is mediated by convergent de novo loss of function of two core flowering time genes: FRI on one island and FLC on the other. Evolutionary reconstructions reveal a case where expansion of the new populations coincided with the emergence and proliferation of these variants, consistent with models of rapid adaptation and evolutionary rescue. Nature Publishing Group UK 2022-03-18 /pmc/articles/PMC8933414/ /pubmed/35304466 http://dx.doi.org/10.1038/s41467-022-28800-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Fulgione, Andrea
Neto, Célia
Elfarargi, Ahmed F.
Tergemina, Emmanuel
Ansari, Shifa
Göktay, Mehmet
Dinis, Herculano
Döring, Nina
Flood, Pádraic J.
Rodriguez-Pacheco, Sofia
Walden, Nora
Koch, Marcus A.
Roux, Fabrice
Hermisson, Joachim
Hancock, Angela M.
Parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages
title Parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages
title_full Parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages
title_fullStr Parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages
title_full_unstemmed Parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages
title_short Parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages
title_sort parallel reduction in flowering time from de novo mutations enable evolutionary rescue in colonizing lineages
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933414/
https://www.ncbi.nlm.nih.gov/pubmed/35304466
http://dx.doi.org/10.1038/s41467-022-28800-z
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