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DNA-based platform for efficient and precisely targeted bioorthogonal catalysis in living systems

As one of the typical bioorthogonal reactions, copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction holds great potential in organic synthesis, bioconjugation, and surface functionalization. However, the toxicity of Cu(I), inefficient catalytic activity, and the lack of cell specific targ...

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Detalles Bibliográficos
Autores principales: You, Yawen, Deng, Qingqing, Wang, Yibo, Sang, Yanjuan, Li, Guangming, Pu, Fang, Ren, Jinsong, Qu, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933418/
https://www.ncbi.nlm.nih.gov/pubmed/35304487
http://dx.doi.org/10.1038/s41467-022-29167-x