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Characterization of protein unfolding by fast cross-linking mass spectrometry using di-ortho-phthalaldehyde cross-linkers

Chemical cross-linking of proteins coupled with mass spectrometry is widely used in protein structural analysis. In this study we develop a class of non-hydrolyzable amine-selective di-ortho-phthalaldehyde (DOPA) cross-linkers, one of which is called DOPA2. Cross-linking of proteins with DOPA2 is 60...

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Detalles Bibliográficos
Autores principales:	Wang, Jian-Hua, Tang, Yu-Liang, Gong, Zhou, Jain, Rohit, Xiao, Fan, Zhou, Yu, Tan, Dan, Li, Qiang, Huang, Niu, Liu, Shu-Qun, Ye, Keqiong, Tang, Chun, Dong, Meng-Qiu, Lei, Xiaoguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933431/ https://www.ncbi.nlm.nih.gov/pubmed/35304446 http://dx.doi.org/10.1038/s41467-022-28879-4

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