CMTM6 inhibits tumor growth and reverses chemoresistance by preventing ubiquitination of p21 in hepatocellular carcinoma

Hepatocellular carcinoma is one of the most common malignancies and has a poor prognosis. The ubiquitin-proteasome pathway is required for the degradation of most short-lived proteins. CMTM6 has been implicated in the progression of various tumors, but its biological function and the underlying mole...

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Detalles Bibliográficos
Autores principales: Huang, Yue, Zhu, Yingqin, Yang, Jieying, Pan, Qiuzhong, Zhao, Jingjing, Song, Mengjia, Yang, Chaopin, Han, Yulong, Tang, Yan, Wang, Qijing, He, Jia, Li, Yongqiang, He, Junyi, Chen, Hao, Weng, Desheng, Xiang, Tong, Xia, Jian Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933468/
https://www.ncbi.nlm.nih.gov/pubmed/35304440
http://dx.doi.org/10.1038/s41419-022-04676-1

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