Tamoxifen treatment ameliorates contractile dysfunction of Duchenne muscular dystrophy stem cell-derived cardiomyocytes on bioengineered substrates

Duchenne muscular dystrophy (DMD) is a progressive genetic myopathy that leads to heart failure from dilated cardiomyopathy by early adulthood. Recent evidence suggests that tamoxifen, a selective estrogen receptor modulator widely used to treat breast cancer, ameliorates DMD cardiomyopathy. However...

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Detalles Bibliográficos
Autores principales: Birnbaum, Foster, Eguchi, Asuka, Pardon, Gaspard, Chang, Alex C. Y., Blau, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933505/
https://www.ncbi.nlm.nih.gov/pubmed/35304486
http://dx.doi.org/10.1038/s41536-022-00214-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933505/
https://www.ncbi.nlm.nih.gov/pubmed/35304486
http://dx.doi.org/10.1038/s41536-022-00214-x

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