Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents

BACKGROUND AND AIMS: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver condition. It is tightly associated with an adverse metabolic phenotype (including obesity and type 2 diabetes) as well as with obstructive sleep apnoea (OSA) of which intermittent hypoxia is a critical c...

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Detalles Bibliográficos
Autores principales: Hazlehurst, Jonathan M., Lim, Teegan Reina, Charlton, Catriona, Miller, Jack J., Gathercole, Laura L., Cornfield, Thomas, Nikolaou, Nikolaos, Harris, Shelley E., Moolla, Ahmad, Othonos, Nantia, Heather, Lisa C., Marjot, Thomas, Tyler, Damian J., Carr, Carolyn, Hodson, Leanne, McKeating, Jane, Tomlinson, Jeremy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933516/
https://www.ncbi.nlm.nih.gov/pubmed/35313531
http://dx.doi.org/10.1016/j.metop.2022.100177

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