Cargando…

Cardiac protection by pirfenidone after myocardial infarction: a bioinformatic analysis

Left ventricular (LV) remodeling after myocardial infarction (MI) is promoted by an intense fibrotic response, which could be targeted by the anti-fibrotic drug pirfenidone. We explored the relationship between protein modulation by pirfenidone and post-MI remodeling, based on molecular information...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aimo, Alberto, Iborra-Egea, Oriol, Martini, Nicola, Galvez-Monton, Carolina, Burchielli, Silvia, Panichella, Giorgia, Passino, Claudio, Emdin, Michele, Bayes-Genis, Antoni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933518/ https://www.ncbi.nlm.nih.gov/pubmed/35304529 http://dx.doi.org/10.1038/s41598-022-08523-3

Ejemplares similares

The Potential Anti-remodeling Effect of Paroxetine After Myocardial Infarction May Be Blunted by Beta-Blockers
por: Iborra-Egea, Oriol, et al.
Publicado: (2022)

Pirfenidone as a novel cardiac protective treatment
por: Aimo, Alberto, et al.
Publicado: (2021)

Different Effects on Protein Expression of CDR132L, an Antisense Inhibitor of miR-132, and Standard Therapies for Myocardial Infarction
por: Iborra-Egea, Oriol, et al.
Publicado: (2022)

Management of heart failure with preserved ejection fraction: from neurohormonal antagonists to empagliflozin
por: Aimo, Alberto, et al.
Publicado: (2022)

Pirfenidone for Idiopathic Pulmonary Fibrosis and Beyond
por: Aimo, Alberto, et al.
Publicado: (2022)

Commentary: A Review of Prognosis Model Associated With Cardiogenic Shock After Acute Myocardial Infarction
por: Iborra-Egea, Oriol, et al.
Publicado: (2022)

iPSC Therapy for Myocardial Infarction in Large Animal Models: Land of Hope and Dreams
por: Martínez-Falguera, Daina, et al.
Publicado: (2021)

A Cell-Enriched Engineered Myocardial Graft Limits Infarct Size and Improves Cardiac Function: Pre-Clinical Study in the Porcine Myocardial Infarction Model
por: Perea-Gil, Isaac, et al.
Publicado: (2016)

Treatment of cardiac fibrosis: from neuro-hormonal inhibitors to CAR-T cell therapy
por: Morfino, Paolo, et al.
Publicado: (2022)

Deep Learning Analyses to Delineate the Molecular Remodeling Process after Myocardial Infarction
por: Iborra-Egea, Oriol, et al.
Publicado: (2021)

Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach
por: Iborra-Egea, Oriol, et al.
Publicado: (2017)

Translational proteomics in cardiogenic shock: from benchmark to bedside
por: Iborra-Egea, Oriol, et al.
Publicado: (2022)

Identification of Temporal and Region-Specific Myocardial Gene Expression Patterns in Response to Infarction in Swine
por: Prat-Vidal, Cristina, et al.
Publicado: (2013)

Mesenchymal Stem Cells Induce Expression of CD73 in Human Monocytes In Vitro and in a Swine Model of Myocardial Infarction In Vivo
por: Monguió-Tortajada, Marta, et al.
Publicado: (2017)

Our Journey Through Advanced Therapies to Reduce Post-Infarct Scarring
por: Roura, Santiago, et al.
Publicado: (2021)

Head-to-head comparison of two engineered cardiac grafts for myocardial repair: From scaffold characterization to pre-clinical testing
por: Perea-Gil, Isaac, et al.
Publicado: (2018)

Bioluminescence imaging: a shining future for cardiac regeneration
por: Roura, Santiago, et al.
Publicado: (2013)

Epigenetic Biomarkers in Cardiovascular Diseases
por: Soler-Botija, Carolina, et al.
Publicado: (2019)

Neoinnervation and neovascularization of acellular pericardial-derived scaffolds in myocardial infarcts
por: Gálvez-Montón, Carolina, et al.
Publicado: (2015)

Amyloid seeding as a disease mechanism and treatment target in transthyretin cardiac amyloidosis
por: Morfino, Paolo, et al.
Publicado: (2022)

Pathophysiological Rationale and Clinical Evidence for Neurohormonal Modulation in Heart Failure with Preserved Ejection Fraction
por: Castiglione, Vincenzo, et al.
Publicado: (2023)

Electromechanical Conditioning of Adult Progenitor Cells Improves Recovery of Cardiac Function After Myocardial Infarction
por: Llucià‐Valldeperas, Aida, et al.
Publicado: (2016)

Atrial amyloidosis: mechanisms and clinical manifestations
por: Vergaro, Giuseppe, et al.
Publicado: (2022)

The role and potential of umbilical cord blood in an era of new therapies: a review
por: Roura, Santiago, et al.
Publicado: (2015)

Impact of Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Cardiovascular Research
por: Roura, Santiago, et al.
Publicado: (2015)

Comparison of two preclinical myocardial infarct models: coronary coil deployment versus surgical ligation
por: Gálvez-Montón, Carolina, et al.
Publicado: (2014)

Mesenchymal stem cells for cardiac repair: are the actors ready for the clinical scenario?
por: Roura, Santiago, et al.
Publicado: (2017)

Intracoronary Delivery of Mitochondria to Prevent Ischemia–Reperfusion Injury: Challenging Pathway From Bench to Bedside
por: Aimo, Alberto, et al.
Publicado: (2020)

Subclinical cardiac damage in cancer patients before chemotherapy
por: Fabiani, Iacopo, et al.
Publicado: (2021)

Noninvasive Assessment of an Engineered Bioactive Graft in Myocardial Infarction: Impact on Cardiac Function and Scar Healing
por: Gálvez‐Montón, Carolina, et al.
Publicado: (2016)

Circulating virome and inflammatory proteome in patients with ST-elevation myocardial infarction and primary ventricular fibrillation
por: Oliveras, Teresa, et al.
Publicado: (2022)

Microencapsulated Insulin-Like Growth Factor-1 therapy improves cardiac function and reduces fibrosis in a porcine acute myocardial infarction model
por: Báez-Díaz, Claudia, et al.
Publicado: (2020)

Transitioning From Preclinical Evidence to Advanced Therapy Medicinal Product: A Spanish Experience
por: Gastelurrutia, Paloma, et al.
Publicado: (2021)

In vivo experience with natural scaffolds for myocardial infarction: the times they are a-changin’
por: Perea-Gil, Isaac, et al.
Publicado: (2015)

Compelling Benefit of Soluble Suppression of Tumorigenicity‐2 in Post–Myocardial Infarction Estimation of Risk: The Time Is Right for Its Routine Use in the Clinic
por: Díez, Javier, et al.
Publicado: (2017)

Acellular cardiac scaffolds enriched with MSC-derived extracellular vesicles limit ventricular remodelling and exert local and systemic immunomodulation in a myocardial infarction porcine model
por: Monguió-Tortajada, Marta, et al.
Publicado: (2022)

Local administration of porcine immunomodulatory, chemotactic and angiogenic extracellular vesicles using engineered cardiac scaffolds for myocardial infarction
por: Monguió-Tortajada, Marta, et al.
Publicado: (2021)

Role of Imaging in Cardiomyopathies
por: Castiglione, Vincenzo, et al.
Publicado: (2023)

Electrophysiological effects of adipose graft transposition procedure (AGTP) on the post-myocardial infarction scar: A multimodal characterization of arrhythmogenic substrate
por: Adeliño, Raquel, et al.
Publicado: (2022)

Extracellular vesicles do not contribute to higher circulating levels of soluble LRP1 in idiopathic dilated cardiomyopathy
por: Roura, Santiago, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_emvhd63v7ui46flc4sfnkg9v3g