Cargando…

Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos

Detalles Bibliográficos
Autores principales: Wei, Yinghui, Li, Zhifang, Xu, Kui, Feng, Hu, Xie, Long, Li, Di, Zuo, Zhenrui, Zhang, Meiling, Xu, Chunlong, Yang, Hui, Zuo, Erwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933521/
https://www.ncbi.nlm.nih.gov/pubmed/35304438
http://dx.doi.org/10.1038/s41421-022-00391-5
_version_ 1784671673747767296
author Wei, Yinghui
Li, Zhifang
Xu, Kui
Feng, Hu
Xie, Long
Li, Di
Zuo, Zhenrui
Zhang, Meiling
Xu, Chunlong
Yang, Hui
Zuo, Erwei
author_facet Wei, Yinghui
Li, Zhifang
Xu, Kui
Feng, Hu
Xie, Long
Li, Di
Zuo, Zhenrui
Zhang, Meiling
Xu, Chunlong
Yang, Hui
Zuo, Erwei
author_sort Wei, Yinghui
collection PubMed
description
format Online
Article
Text
id pubmed-8933521
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Springer Singapore
record_format MEDLINE/PubMed
spelling pubmed-89335212022-04-01 Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos Wei, Yinghui Li, Zhifang Xu, Kui Feng, Hu Xie, Long Li, Di Zuo, Zhenrui Zhang, Meiling Xu, Chunlong Yang, Hui Zuo, Erwei Cell Discov Correspondence Springer Singapore 2022-03-18 /pmc/articles/PMC8933521/ /pubmed/35304438 http://dx.doi.org/10.1038/s41421-022-00391-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Correspondence
Wei, Yinghui
Li, Zhifang
Xu, Kui
Feng, Hu
Xie, Long
Li, Di
Zuo, Zhenrui
Zhang, Meiling
Xu, Chunlong
Yang, Hui
Zuo, Erwei
Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos
title Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos
title_full Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos
title_fullStr Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos
title_full_unstemmed Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos
title_short Mitochondrial base editor DdCBE causes substantial DNA off-target editing in nuclear genome of embryos
title_sort mitochondrial base editor ddcbe causes substantial dna off-target editing in nuclear genome of embryos
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933521/
https://www.ncbi.nlm.nih.gov/pubmed/35304438
http://dx.doi.org/10.1038/s41421-022-00391-5
work_keys_str_mv AT weiyinghui mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos
AT lizhifang mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos
AT xukui mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos
AT fenghu mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos
AT xielong mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos
AT lidi mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos
AT zuozhenrui mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos
AT zhangmeiling mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos
AT xuchunlong mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos
AT yanghui mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos
AT zuoerwei mitochondrialbaseeditorddcbecausessubstantialdnaofftargeteditinginnucleargenomeofembryos