Protocol for assessing auditory brainstem response in mice using a four-channel recording system

Evaluating auditory sensitivity is critical to hearing research, particularly to that focusing on hearing impairment. Auditory brainstem response recording is frequently used in mice to assess auditory sensitivity and is an approach superior to the traditional techniques. Here, we describe a protoco...

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Detalles Bibliográficos
Autores principales: Zeng, Lingling, Zhou, Wen, Bing, Dan, Xie, Li, Wang, Xiaodi, Zhang, Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933526/
https://www.ncbi.nlm.nih.gov/pubmed/35313709
http://dx.doi.org/10.1016/j.xpro.2022.101251
Descripción
Sumario:Evaluating auditory sensitivity is critical to hearing research, particularly to that focusing on hearing impairment. Auditory brainstem response recording is frequently used in mice to assess auditory sensitivity and is an approach superior to the traditional techniques. Here, we describe a protocol for recording ABR in mice using four-channel equipment. We detail the procedures of animal preparation, the setup of the ABR recording system, the click- and tone burst-evoked ABR recordings, and data analysis.

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