Protocol for assessing auditory brainstem response in mice using a four-channel recording system

Evaluating auditory sensitivity is critical to hearing research, particularly to that focusing on hearing impairment. Auditory brainstem response recording is frequently used in mice to assess auditory sensitivity and is an approach superior to the traditional techniques. Here, we describe a protoco...

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Detalles Bibliográficos
Autores principales: Zeng, Lingling, Zhou, Wen, Bing, Dan, Xie, Li, Wang, Xiaodi, Zhang, Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933526/
https://www.ncbi.nlm.nih.gov/pubmed/35313709
http://dx.doi.org/10.1016/j.xpro.2022.101251
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author Zeng, Lingling
Zhou, Wen
Bing, Dan
Xie, Li
Wang, Xiaodi
Zhang, Guo
author_facet Zeng, Lingling
Zhou, Wen
Bing, Dan
Xie, Li
Wang, Xiaodi
Zhang, Guo
author_sort Zeng, Lingling
collection PubMed
description Evaluating auditory sensitivity is critical to hearing research, particularly to that focusing on hearing impairment. Auditory brainstem response recording is frequently used in mice to assess auditory sensitivity and is an approach superior to the traditional techniques. Here, we describe a protocol for recording ABR in mice using four-channel equipment. We detail the procedures of animal preparation, the setup of the ABR recording system, the click- and tone burst-evoked ABR recordings, and data analysis.
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spelling pubmed-89335262022-03-20 Protocol for assessing auditory brainstem response in mice using a four-channel recording system Zeng, Lingling Zhou, Wen Bing, Dan Xie, Li Wang, Xiaodi Zhang, Guo STAR Protoc Protocol Evaluating auditory sensitivity is critical to hearing research, particularly to that focusing on hearing impairment. Auditory brainstem response recording is frequently used in mice to assess auditory sensitivity and is an approach superior to the traditional techniques. Here, we describe a protocol for recording ABR in mice using four-channel equipment. We detail the procedures of animal preparation, the setup of the ABR recording system, the click- and tone burst-evoked ABR recordings, and data analysis. Elsevier 2022-03-16 /pmc/articles/PMC8933526/ /pubmed/35313709 http://dx.doi.org/10.1016/j.xpro.2022.101251 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Protocol
Zeng, Lingling
Zhou, Wen
Bing, Dan
Xie, Li
Wang, Xiaodi
Zhang, Guo
Protocol for assessing auditory brainstem response in mice using a four-channel recording system
title Protocol for assessing auditory brainstem response in mice using a four-channel recording system
title_full Protocol for assessing auditory brainstem response in mice using a four-channel recording system
title_fullStr Protocol for assessing auditory brainstem response in mice using a four-channel recording system
title_full_unstemmed Protocol for assessing auditory brainstem response in mice using a four-channel recording system
title_short Protocol for assessing auditory brainstem response in mice using a four-channel recording system
title_sort protocol for assessing auditory brainstem response in mice using a four-channel recording system
topic Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933526/
https://www.ncbi.nlm.nih.gov/pubmed/35313709
http://dx.doi.org/10.1016/j.xpro.2022.101251
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