Cargando…
Molecular dynamics of G6PD variants from sub-Saharan Africa
Precision medicine uses genomic guidance to improve drug treatment safety and efficacy. Prior knowledge of genetic variant impact can enable such strategies, but current knowledge of African variants remains scarce. G6PD variants are linked to haemolytic adverse effects for a number of drugs commonl...
Autores principales: | Batista da Rocha, Jorge, Othman, Houcemeddine, Hazelhurst, Scott |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933681/ https://www.ncbi.nlm.nih.gov/pubmed/35313643 http://dx.doi.org/10.1016/j.bbrep.2022.101236 |
Ejemplares similares
-
G6PD variant distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19
por: da Rocha, Jorge, et al.
Publicado: (2020) -
Single Nucleotide Polymorphism Induces Divergent Dynamic Patterns in CYP3A5: A Microsecond Scale Biomolecular Simulation of Variants Identified in Sub-Saharan African Populations
por: Othman, Houcemeddine, et al.
Publicado: (2021) -
G6PD distribution in sub-Saharan Africa and potential risks of using chloroquine/hydroxychloroquine based treatments for COVID-19
por: da Rocha, Jorge E. B., et al.
Publicado: (2021) -
SWAAT Bioinformatics Workflow for Protein Structure-Based Annotation of ADME Gene Variants
por: Othman, Houcemeddine, et al.
Publicado: (2022) -
The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations
por: da Rocha, Jorge E. B., et al.
Publicado: (2021)