PRMT5 regulates ATF4 transcript splicing and oxidative stress response

Protein methyltransferase 5 (PRMT5) symmetrically dimethylates arginine residues leading to regulation of transcription and splicing programs. Although PRMT5 has emerged as an attractive oncology target, the molecular determinants of PRMT5 dependency in cancer remain incompletely understood. Our tra...

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Detalles Bibliográficos
Autores principales: Szewczyk, Magdalena M., Luciani, Genna M., Vu, Victoria, Murison, Alex, Dilworth, David, Barghout, Samir H., Lupien, Mathieu, Arrowsmith, Cheryl H., Minden, Mark D., Barsyte-Lovejoy, Dalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933703/
https://www.ncbi.nlm.nih.gov/pubmed/35305370
http://dx.doi.org/10.1016/j.redox.2022.102282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933703/
https://www.ncbi.nlm.nih.gov/pubmed/35305370
http://dx.doi.org/10.1016/j.redox.2022.102282

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