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ATP allosterically stabilizes integrin-linked kinase for efficient force generation

Focal adhesions link the actomyosin cytoskeleton to the extracellular matrix regulating cell adhesion, shape, and migration. Adhesions are dynamically assembled and disassembled in response to extrinsic and intrinsic forces, but how the essential adhesion component integrin-linked kinase (ILK) dynam...

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Detalles Bibliográficos
Autores principales:	Martin, Isabel M., Nava, Michele M., Wickström, Sara A., Gräter, Frauke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Physical Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933812/ https://www.ncbi.nlm.nih.gov/pubmed/35259013 http://dx.doi.org/10.1073/pnas.2106098119

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