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Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses
BACKGROUND: Acute lung injury (ALI) has received considerable attention in the field of intensive care as it is associated with a high mortality rate. Obacunone (OB), widely found in citrus fruits, is a natural bioactive compound with anti-inflammatory and antioxidant activities. However, it is not...
Autores principales: | Li, Jin, Deng, Shi-hua, Li, Jing, Li, Li, Zhang, Feng, Zou, Ye, Wu, Dong-ming, Xu, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8933916/ https://www.ncbi.nlm.nih.gov/pubmed/35305560 http://dx.doi.org/10.1186/s11658-022-00318-8 |
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