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Clinical features of nursing and healthcare-associated pneumonia due to COVID-19

INTRODUCTION: The objective of this study was to clarify the clinical differences between nursing and healthcare-associated pneumonia (NHCAP) and community-acquired pneumonia (CAP) due to COVID-19. We also investigated the clinical characteristics to determine whether there is a difference between t...

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Autores principales: Miyashita, Naoyuki, Nakamori, Yasushi, Ogata, Makoto, Fukuda, Naoki, Yamura, Akihisa, Ishiura, Yoshihisa, Nomura, Shosaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934135/
https://www.ncbi.nlm.nih.gov/pubmed/35317976
http://dx.doi.org/10.1016/j.jiac.2022.03.010
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author Miyashita, Naoyuki
Nakamori, Yasushi
Ogata, Makoto
Fukuda, Naoki
Yamura, Akihisa
Ishiura, Yoshihisa
Nomura, Shosaku
author_facet Miyashita, Naoyuki
Nakamori, Yasushi
Ogata, Makoto
Fukuda, Naoki
Yamura, Akihisa
Ishiura, Yoshihisa
Nomura, Shosaku
author_sort Miyashita, Naoyuki
collection PubMed
description INTRODUCTION: The objective of this study was to clarify the clinical differences between nursing and healthcare-associated pneumonia (NHCAP) and community-acquired pneumonia (CAP) due to COVID-19. We also investigated the clinical characteristics to determine whether there is a difference between the variant and non-variant strain in patients with NHCAP due to COVID-19. In addition, we analyzed the clinical outcomes in NHCAP patients with mental disorders who were hospitalized in a medical institution for treatment of mental illness. METHODS: This study was conducted at five institutions and assessed a total of 836 patients with COVID-19 pneumonia (154 cases were classified as NHCAP and 335 had lineage B.1.1.7.). RESULTS: No differences in patient background, clinical findings, disease severity, or outcomes were observed in patients with NHCAP between the non-B.1.1.7 group and B.1.1.7 group. The median age, frequency of comorbid illness, rates of intensive care unit stay, and mortality rate were significantly higher in patients with NHCAP than in those with CAP. Among the patients with NHCAP, the mortality rate was highest at 37.5% in patients with recent cancer treatment, followed by elderly or disabled patients receiving nursing care (24.3%), residents of care facilities (23.0%), patients receiving dialysis (13.6%), and patients in mental hospitals (9.4%). CONCLUSIONS: Our results demonstrated that there were many differences in the clinical characteristics between NHCAP patients and CAP patients due to COVID-19. It is necessary to consider the prevention and treatment content depending on the presence or absence of applicable criteria for NHCAP.
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spelling pubmed-89341352022-03-21 Clinical features of nursing and healthcare-associated pneumonia due to COVID-19 Miyashita, Naoyuki Nakamori, Yasushi Ogata, Makoto Fukuda, Naoki Yamura, Akihisa Ishiura, Yoshihisa Nomura, Shosaku J Infect Chemother Original Article INTRODUCTION: The objective of this study was to clarify the clinical differences between nursing and healthcare-associated pneumonia (NHCAP) and community-acquired pneumonia (CAP) due to COVID-19. We also investigated the clinical characteristics to determine whether there is a difference between the variant and non-variant strain in patients with NHCAP due to COVID-19. In addition, we analyzed the clinical outcomes in NHCAP patients with mental disorders who were hospitalized in a medical institution for treatment of mental illness. METHODS: This study was conducted at five institutions and assessed a total of 836 patients with COVID-19 pneumonia (154 cases were classified as NHCAP and 335 had lineage B.1.1.7.). RESULTS: No differences in patient background, clinical findings, disease severity, or outcomes were observed in patients with NHCAP between the non-B.1.1.7 group and B.1.1.7 group. The median age, frequency of comorbid illness, rates of intensive care unit stay, and mortality rate were significantly higher in patients with NHCAP than in those with CAP. Among the patients with NHCAP, the mortality rate was highest at 37.5% in patients with recent cancer treatment, followed by elderly or disabled patients receiving nursing care (24.3%), residents of care facilities (23.0%), patients receiving dialysis (13.6%), and patients in mental hospitals (9.4%). CONCLUSIONS: Our results demonstrated that there were many differences in the clinical characteristics between NHCAP patients and CAP patients due to COVID-19. It is necessary to consider the prevention and treatment content depending on the presence or absence of applicable criteria for NHCAP. Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. 2022-07 2022-03-19 /pmc/articles/PMC8934135/ /pubmed/35317976 http://dx.doi.org/10.1016/j.jiac.2022.03.010 Text en © 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Article
Miyashita, Naoyuki
Nakamori, Yasushi
Ogata, Makoto
Fukuda, Naoki
Yamura, Akihisa
Ishiura, Yoshihisa
Nomura, Shosaku
Clinical features of nursing and healthcare-associated pneumonia due to COVID-19
title Clinical features of nursing and healthcare-associated pneumonia due to COVID-19
title_full Clinical features of nursing and healthcare-associated pneumonia due to COVID-19
title_fullStr Clinical features of nursing and healthcare-associated pneumonia due to COVID-19
title_full_unstemmed Clinical features of nursing and healthcare-associated pneumonia due to COVID-19
title_short Clinical features of nursing and healthcare-associated pneumonia due to COVID-19
title_sort clinical features of nursing and healthcare-associated pneumonia due to covid-19
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934135/
https://www.ncbi.nlm.nih.gov/pubmed/35317976
http://dx.doi.org/10.1016/j.jiac.2022.03.010
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