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New bis hydrazone: Synthesis, X-ray crystal structure, DFT computations, conformational study and in silico study of the inhibition activity of SARS-CoV-2

The aim of this work was to synthesize new bis hydrazone derived from benzil in good yield, namely: (1Z,2Z)-1,2-bis (3-Chlorophenyl Hydrazino) Benzil, encoded by 3-Cl BHB. The benzil (or 1,2-diphenyl ethanedione) reacts with 3-Cl phenyl hydrazine by reflux method using ethanol as solvent to obtain t...

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Detalles Bibliográficos
Autores principales:	Tabbiche, Abdelkader, Bouchama, Abdelaziz, Chafai, Nadjib, Zaidi, Farouk, Chiter, Chaabane, Yahiaoui, Messaoud, Abiza, Abdellah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934244/ https://www.ncbi.nlm.nih.gov/pubmed/35345533 http://dx.doi.org/10.1016/j.molstruc.2022.132865

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