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Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room

Disinfection of hospital facilities and ambulances is an important issue for breaking the chain of transmission of viral pathogens. Hydrogen peroxide has provided promising results in laboratory assays. Here, we evaluate the efficacy of a hydrogen peroxide nebulizer for the inactivation of surrogate...

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Detalles Bibliográficos
Autores principales: Estienney, Marie, Daval-Frerot, Philippe, Aho-Glélé, Ludwig-Serge, Piroth, Lionel, Stabile, Pascal, Gerbet, Jean-Yves, Rouleau, Romain, de Rougemont, Alexis, Belliot, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934245/
https://www.ncbi.nlm.nih.gov/pubmed/35306645
http://dx.doi.org/10.1007/s12560-022-09519-y
Descripción
Sumario:Disinfection of hospital facilities and ambulances is an important issue for breaking the chain of transmission of viral pathogens. Hydrogen peroxide has provided promising results in laboratory assays. Here, we evaluate the efficacy of a hydrogen peroxide nebulizer for the inactivation of surrogate MS2 bacteriophage and murine norovirus (MNV) in a patient waiting room and the fully equipped cabin of a medical ambulance. We observed an average 3 log(10) titer reduction in both settings, which represents the destruction of over 10(6) and 10(9) infectious particles of MNV and MS2 per cm(2), respectively. The potential for viral exposure is high for health workers when disinfecting confined and cluttered spaces, so the use of a hydrogen peroxide mist might offer an affordable and efficient solution to minimize the risk of viral contaminations.