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Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room

Disinfection of hospital facilities and ambulances is an important issue for breaking the chain of transmission of viral pathogens. Hydrogen peroxide has provided promising results in laboratory assays. Here, we evaluate the efficacy of a hydrogen peroxide nebulizer for the inactivation of surrogate...

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Autores principales: Estienney, Marie, Daval-Frerot, Philippe, Aho-Glélé, Ludwig-Serge, Piroth, Lionel, Stabile, Pascal, Gerbet, Jean-Yves, Rouleau, Romain, de Rougemont, Alexis, Belliot, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934245/
https://www.ncbi.nlm.nih.gov/pubmed/35306645
http://dx.doi.org/10.1007/s12560-022-09519-y
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author Estienney, Marie
Daval-Frerot, Philippe
Aho-Glélé, Ludwig-Serge
Piroth, Lionel
Stabile, Pascal
Gerbet, Jean-Yves
Rouleau, Romain
de Rougemont, Alexis
Belliot, Gaël
author_facet Estienney, Marie
Daval-Frerot, Philippe
Aho-Glélé, Ludwig-Serge
Piroth, Lionel
Stabile, Pascal
Gerbet, Jean-Yves
Rouleau, Romain
de Rougemont, Alexis
Belliot, Gaël
author_sort Estienney, Marie
collection PubMed
description Disinfection of hospital facilities and ambulances is an important issue for breaking the chain of transmission of viral pathogens. Hydrogen peroxide has provided promising results in laboratory assays. Here, we evaluate the efficacy of a hydrogen peroxide nebulizer for the inactivation of surrogate MS2 bacteriophage and murine norovirus (MNV) in a patient waiting room and the fully equipped cabin of a medical ambulance. We observed an average 3 log(10) titer reduction in both settings, which represents the destruction of over 10(6) and 10(9) infectious particles of MNV and MS2 per cm(2), respectively. The potential for viral exposure is high for health workers when disinfecting confined and cluttered spaces, so the use of a hydrogen peroxide mist might offer an affordable and efficient solution to minimize the risk of viral contaminations.
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spelling pubmed-89342452022-03-21 Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room Estienney, Marie Daval-Frerot, Philippe Aho-Glélé, Ludwig-Serge Piroth, Lionel Stabile, Pascal Gerbet, Jean-Yves Rouleau, Romain de Rougemont, Alexis Belliot, Gaël Food Environ Virol Brief Communication Disinfection of hospital facilities and ambulances is an important issue for breaking the chain of transmission of viral pathogens. Hydrogen peroxide has provided promising results in laboratory assays. Here, we evaluate the efficacy of a hydrogen peroxide nebulizer for the inactivation of surrogate MS2 bacteriophage and murine norovirus (MNV) in a patient waiting room and the fully equipped cabin of a medical ambulance. We observed an average 3 log(10) titer reduction in both settings, which represents the destruction of over 10(6) and 10(9) infectious particles of MNV and MS2 per cm(2), respectively. The potential for viral exposure is high for health workers when disinfecting confined and cluttered spaces, so the use of a hydrogen peroxide mist might offer an affordable and efficient solution to minimize the risk of viral contaminations. Springer US 2022-03-20 2022 /pmc/articles/PMC8934245/ /pubmed/35306645 http://dx.doi.org/10.1007/s12560-022-09519-y Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Brief Communication
Estienney, Marie
Daval-Frerot, Philippe
Aho-Glélé, Ludwig-Serge
Piroth, Lionel
Stabile, Pascal
Gerbet, Jean-Yves
Rouleau, Romain
de Rougemont, Alexis
Belliot, Gaël
Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room
title Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room
title_full Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room
title_fullStr Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room
title_full_unstemmed Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room
title_short Use of a Hydrogen Peroxide Nebulizer for Viral Disinfection of Emergency Ambulance and Hospital Waiting Room
title_sort use of a hydrogen peroxide nebulizer for viral disinfection of emergency ambulance and hospital waiting room
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934245/
https://www.ncbi.nlm.nih.gov/pubmed/35306645
http://dx.doi.org/10.1007/s12560-022-09519-y
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