Amyloid β / PKC-dependent alterations in NMDA receptor composition are detected in early stages of Alzheimer´s disease

Amyloid beta (Aβ)-mediated synapse dysfunction is an early event in Alzheimer’s disease (AD) pathogenesis and previous studies suggest that NMDA receptor (NMDAR) dysregulation may contribute to these pathological effects. Although Aβ peptides impair NMDAR expression and activity, the mechanisms medi...

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Detalles Bibliográficos
Autores principales: Ortiz-Sanz, Carolina, Balantzategi, Uxue, Quintela-López, Tania, Ruiz, Asier, Luchena, Celia, Zuazo-Ibarra, Jone, Capetillo-Zarate, Estibaliz, Matute, Carlos, Zugaza, José L., Alberdi, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934345/
https://www.ncbi.nlm.nih.gov/pubmed/35306512
http://dx.doi.org/10.1038/s41419-022-04687-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934345/
https://www.ncbi.nlm.nih.gov/pubmed/35306512
http://dx.doi.org/10.1038/s41419-022-04687-y

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