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A one-dimensional parameter-free model for carcinogenesis in gene expression space
A small portion of a tissue defines a microstate in gene expression space. Mutations, epigenetic events or external factors cause microstate displacements which are modeled by combining small independent gene expression variations and large Levy jumps, resulting from the collective variations of a s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934350/ https://www.ncbi.nlm.nih.gov/pubmed/35306505 http://dx.doi.org/10.1038/s41598-022-08502-8 |