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Pyruvate kinase L/R links metabolism dysfunction to neuroendocrine differentiation of prostate cancer by ZBTB10 deficiency

Neuroendocrine differentiation (NED) frequently occurs in androgen-deprivation therapy (ADT)-resistant prostate cancer (PCa) and is typically associated with metabolic pathway alterations, acquisition of lineage plasticity, and malignancy. There is no conventional therapeutic approach for PCa patien...

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Detalles Bibliográficos
Autores principales:	Wen, Yu-Ching, Chen, Wei-Yu, Tram, Van Thi Ngoc, Yeh, Hsiu-Lien, Chen, Wei-Hao, Jiang, Kuo-Ching, Abou-Kheir, Wassim, Huang, Jiaoti, Hsiao, Michael, Liu, Yen-Nien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934352/ https://www.ncbi.nlm.nih.gov/pubmed/35306527 http://dx.doi.org/10.1038/s41419-022-04694-z

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