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Detection and characterization of simvastatin and its metabolites in rat tissues and biological fluids using MALDI high resolution mass spectrometry approach

Simvastatin (SV) is a hypolipidemic agent, and it is the 2nd most widely prescribed lipid-lowering drug. Here, the detection and characterization of SV and its metabolites was studied in selected organs/tissues (lung, liver, brain, heart and kidney) and biological samples (blood, urine and feces) of...

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Detalles Bibliográficos
Autores principales: Yin, Wencui, Al-Wabli, Reem I., Attwa, Mohamed W., Rahman, A. F. M. Motiur, Kadi, Adnan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934354/
https://www.ncbi.nlm.nih.gov/pubmed/35306510
http://dx.doi.org/10.1038/s41598-022-08804-x

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