Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells

The eukaryotic genome is folded into higher-order conformation accompanied with constrained dynamics for coordinated genome functions. However, the molecular machinery underlying these hierarchically organized three-dimensional (3D) chromatin architecture and dynamics remains poorly understood. Here...

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Detalles Bibliográficos
Autores principales: Chang, Lei, Li, Mengfan, Shao, Shipeng, Li, Chen, Ai, Shanshan, Xue, Boxin, Hou, Yingping, Zhang, Yiwen, Li, Ruifeng, Fan, Xiaoying, He, Aibin, Li, Cheng, Sun, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934373/
https://www.ncbi.nlm.nih.gov/pubmed/33155082
http://dx.doi.org/10.1007/s13238-020-00794-8

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