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METTL14-mediated N(6)-methyladenosine modification of ITGB4 mRNA inhibits metastasis of clear cell renal cell carcinoma

BACKGROUND: Integrin β4 (ITGB4) participates in tumorigenesis and progression of several malignancies, but its role and related mechanisms in clear cell renal cell carcinoma (ccRCC) remain unclear. METHODS: Quantitative real-time PCR (qRT-PCR), western blot and immunohistochemistry were used to dete...

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Detalles Bibliográficos
Autores principales:	Liu, Zhuonan, Sun, Tianshui, Piao, Chiyuan, Zhang, Zhe, Kong, Chuize
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934459/ https://www.ncbi.nlm.nih.gov/pubmed/35305660 http://dx.doi.org/10.1186/s12964-022-00831-5

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