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H(2)O(2)-responsive VEGF/NGF gene co-delivery nano-system achieves stable vascularization in ischemic hindlimbs

Peripheral vascular disease (PVD) is a common clinical manifestation of atherosclerosis. Vascular endothelial growth factor (VEGF) gene therapy is a promising approach for PVD treatment. However, due to single-gene therapy limitations and high H(2)O(2) pathological microenvironment, VEGF gene therap...

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Detalles Bibliográficos
Autores principales: Chen, Youlu, Chen, Zuoguan, Duan, Jianwei, Gui, Liang, Li, Huiyang, Liang, Xiaoyu, Tian, Xinxin, Liu, Kaijing, Li, Yongjun, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934504/
https://www.ncbi.nlm.nih.gov/pubmed/35305670
http://dx.doi.org/10.1186/s12951-022-01328-6

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