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Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus

PURPOSE: The purpose of this study was to assess the impact of different intracorneal ring segments (ICRS) combinations on corneal morphology and visual performance on patients with keratoconus. METHODS: A total of 124 eyes from 96 patients who underwent ICRS surgery were analyzed and classified int...

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Autores principales: Alejandre, Nicolas, Pérez-Merino, Pablo, Velarde, Gonzalo, Jiménez-Alfaro, Ignacio, Marcos, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934543/
https://www.ncbi.nlm.nih.gov/pubmed/35289835
http://dx.doi.org/10.1167/tvst.11.3.19
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author Alejandre, Nicolas
Pérez-Merino, Pablo
Velarde, Gonzalo
Jiménez-Alfaro, Ignacio
Marcos, Susana
author_facet Alejandre, Nicolas
Pérez-Merino, Pablo
Velarde, Gonzalo
Jiménez-Alfaro, Ignacio
Marcos, Susana
author_sort Alejandre, Nicolas
collection PubMed
description PURPOSE: The purpose of this study was to assess the impact of different intracorneal ring segments (ICRS) combinations on corneal morphology and visual performance on patients with keratoconus. METHODS: A total of 124 eyes from 96 patients who underwent ICRS surgery were analyzed and classified into 7 groups based on ICRS disposition and the diameter of the surgical zone (5- and 6-mm). Pre- and postoperative complete ophthalmological examinations were conducted. Corneal geometry, volume, and symmetry were studied. Zernike polynomials were used to build a virtual ray-tracing model to evaluate optical aberrations and the Visual Strehl (VS). RESULTS: ICRS induced significant flattening across the cornea, being more pronounced on the anterior (+0.38 mm, P < 0.001) than on the posterior (+0.15 mm, P < 0.001) corneal radius. Asphericity experienced a larger change for a 6-mm surgical zone diameter (from −1.23 ± 1.1 to −1.86 ± 1.2, P < 0.001) than for a 5-mm zone (from −1.99 ± 1.1 to −2.10 ± 1.5, P = 0.536). Mean astigmatism was reduced by 2.05 D (P < 0.001). Combination four was the most effective in reducing astigmatism. Coma decreased by 30% on average and combination one produced an average reduction by 51% (P < 0.05). Patients experienced significant improvement in visual performance, best corrected visual acuity increased from 0.57 ± 0.21 to 0.69 ± 0.21 and VS changed from 0.049 ± 0.02 to 0.065 ± 0.041. CONCLUSIONS: ICRS combinations implanted within 5 mm diameter zone are more effective in flattening the cornea, whereas those implanted on 6 mm diameter are as effective in reducing astigmatism and are a good choice if the asymmetry and the intended flattening are smaller. Combinations with asymmetrical implants are the best option to regularize corneal surface. TRANSLATIONAL RELEVANCE: This study uses methods and metrics of optical research applied to daily clinical practice.
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spelling pubmed-89345432022-03-21 Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus Alejandre, Nicolas Pérez-Merino, Pablo Velarde, Gonzalo Jiménez-Alfaro, Ignacio Marcos, Susana Transl Vis Sci Technol Article PURPOSE: The purpose of this study was to assess the impact of different intracorneal ring segments (ICRS) combinations on corneal morphology and visual performance on patients with keratoconus. METHODS: A total of 124 eyes from 96 patients who underwent ICRS surgery were analyzed and classified into 7 groups based on ICRS disposition and the diameter of the surgical zone (5- and 6-mm). Pre- and postoperative complete ophthalmological examinations were conducted. Corneal geometry, volume, and symmetry were studied. Zernike polynomials were used to build a virtual ray-tracing model to evaluate optical aberrations and the Visual Strehl (VS). RESULTS: ICRS induced significant flattening across the cornea, being more pronounced on the anterior (+0.38 mm, P < 0.001) than on the posterior (+0.15 mm, P < 0.001) corneal radius. Asphericity experienced a larger change for a 6-mm surgical zone diameter (from −1.23 ± 1.1 to −1.86 ± 1.2, P < 0.001) than for a 5-mm zone (from −1.99 ± 1.1 to −2.10 ± 1.5, P = 0.536). Mean astigmatism was reduced by 2.05 D (P < 0.001). Combination four was the most effective in reducing astigmatism. Coma decreased by 30% on average and combination one produced an average reduction by 51% (P < 0.05). Patients experienced significant improvement in visual performance, best corrected visual acuity increased from 0.57 ± 0.21 to 0.69 ± 0.21 and VS changed from 0.049 ± 0.02 to 0.065 ± 0.041. CONCLUSIONS: ICRS combinations implanted within 5 mm diameter zone are more effective in flattening the cornea, whereas those implanted on 6 mm diameter are as effective in reducing astigmatism and are a good choice if the asymmetry and the intended flattening are smaller. Combinations with asymmetrical implants are the best option to regularize corneal surface. TRANSLATIONAL RELEVANCE: This study uses methods and metrics of optical research applied to daily clinical practice. The Association for Research in Vision and Ophthalmology 2022-03-15 /pmc/articles/PMC8934543/ /pubmed/35289835 http://dx.doi.org/10.1167/tvst.11.3.19 Text en Copyright 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
spellingShingle Article
Alejandre, Nicolas
Pérez-Merino, Pablo
Velarde, Gonzalo
Jiménez-Alfaro, Ignacio
Marcos, Susana
Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus
title Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus
title_full Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus
title_fullStr Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus
title_full_unstemmed Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus
title_short Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus
title_sort optical evaluation of intracorneal ring segment surgery in keratoconus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934543/
https://www.ncbi.nlm.nih.gov/pubmed/35289835
http://dx.doi.org/10.1167/tvst.11.3.19
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