Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials

In this letter we raise several concerns regarding the interesting article by Walter and Krämer about rhomb-encephalitis as a complication two months after the vaccination with an mRNA-based SARS-CoV_2 vaccine. The causal link between the vaccination and encephalitis remained unproven, a SARS-CoV-2...

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Autores principales: Finsterer, Josef, Scorza, Fulvio A., Scorza, Carla A., Fiorini, Ana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934598/
https://www.ncbi.nlm.nih.gov/pubmed/35307038
http://dx.doi.org/10.1186/s42466-022-00178-9
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author Finsterer, Josef
Scorza, Fulvio A.
Scorza, Carla A.
Fiorini, Ana C.
author_facet Finsterer, Josef
Scorza, Fulvio A.
Scorza, Carla A.
Fiorini, Ana C.
author_sort Finsterer, Josef
collection PubMed
description In this letter we raise several concerns regarding the interesting article by Walter and Krämer about rhomb-encephalitis as a complication two months after the vaccination with an mRNA-based SARS-CoV_2 vaccine. The causal link between the vaccination and encephalitis remained unproven, a SARS-CoV-2 infection, Bickerstaff encephalitis were not excluded, the MRI rather suggests brainstem-encephlaitis than pure rhomb-encephalitis, and the cerebro-spinal fluid was not investigated for cytokines or glial markers. Neurologists are called to make all available effort to convincingly evaluate the etiology and the pathophysiological background of an undetermined condition.
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spelling pubmed-89345982022-03-21 Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials Finsterer, Josef Scorza, Fulvio A. Scorza, Carla A. Fiorini, Ana C. Neurol Res Pract Letter to the Editor In this letter we raise several concerns regarding the interesting article by Walter and Krämer about rhomb-encephalitis as a complication two months after the vaccination with an mRNA-based SARS-CoV_2 vaccine. The causal link between the vaccination and encephalitis remained unproven, a SARS-CoV-2 infection, Bickerstaff encephalitis were not excluded, the MRI rather suggests brainstem-encephlaitis than pure rhomb-encephalitis, and the cerebro-spinal fluid was not investigated for cytokines or glial markers. Neurologists are called to make all available effort to convincingly evaluate the etiology and the pathophysiological background of an undetermined condition. BioMed Central 2022-03-21 /pmc/articles/PMC8934598/ /pubmed/35307038 http://dx.doi.org/10.1186/s42466-022-00178-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Letter to the Editor
Finsterer, Josef
Scorza, Fulvio A.
Scorza, Carla A.
Fiorini, Ana C.
Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials
title Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials
title_full Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials
title_fullStr Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials
title_full_unstemmed Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials
title_short Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials
title_sort diagnosing sars-cov-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934598/
https://www.ncbi.nlm.nih.gov/pubmed/35307038
http://dx.doi.org/10.1186/s42466-022-00178-9
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