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HnRNP D activates production of HPV16 E1 and E6 mRNAs by promoting intron retention

Human papillomavirus type 16 (HPV16) E1 and E6 proteins are produced from mRNAs with retained introns, but it has been unclear how these mRNAs are generated. Here, we report that hnRNP D act as a splicing inhibitor of HPV16 E1/E2- and E6/E7-mRNAs thereby generating intron-containing E1- and E6-mRNAs...

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Detalles Bibliográficos
Autores principales:	Cui, Xiaoxu, Hao, Chengyu, Gong, Lijing, Kajitani, Naoko, Schwartz, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934624/ https://www.ncbi.nlm.nih.gov/pubmed/35234917 http://dx.doi.org/10.1093/nar/gkac132

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