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The acetyltransferase p300 is recruited in trans to multiple enhancer sites by lncSmad7
The histone acetyltransferase p300 (also known as KAT3B) is a general transcriptional coactivator that introduces the H3K27ac mark on enhancers triggering their activation and gene transcription. Genome-wide screenings demonstrated that a large fraction of long non-coding RNAs (lncRNAs) plays a role...
Autores principales: | Maldotti, Mara, Lauria, Andrea, Anselmi, Francesca, Molineris, Ivan, Tamburrini, Annalaura, Meng, Guohua, Polignano, Isabelle Laurence, Scrivano, Mirko Giuseppe, Campestre, Fabiola, Simon, Lisa Marie, Rapelli, Stefania, Morandi, Edoardo, Incarnato, Danny, Oliviero, Salvatore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934626/ https://www.ncbi.nlm.nih.gov/pubmed/35137201 http://dx.doi.org/10.1093/nar/gkac083 |
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